2025-01-272025-01-272011-012025-01-27Martín Banderas, L., Sáez-Fernández, E.,...,Arias, J.L. (2025). Dataset of Biocompatible gemcitabine-based nanomedicine engineered by Flow Focusing® for efficient antitumor activity. idUS (Depósito de Investigación de la Universidad de Sevilla). https://doi.org/10.12795/11441/167588.https://hdl.handle.net/11441/167588This dataset corresponds to the article "Biocompatible gemcitabine-based nanomedicine engineered by Flow Focusing® for efficient antitumor activity." It includes experimental data on the preparation and characterization of gemcitabine-loaded PLGA nanoparticles produced by two synthesis methods: double emulsion/solvent evaporation (DE/SEV) and Flow Focusing® (FF). The data encompass zeta potential, drug loading, encapsulation efficiency, drug release profiles and in vitro antitumor activity against MCF-7 cells.A single Excel file with each sheet collecting the data corresponding to a figure or table: -Figure 3: Data corresponding to manuscript Figure 3 on NPs encapsulation efficiency and gemcitabine loading obtained with both methodologies using different values of initial loading. -Figure 4: Data corresponding to manuscript Figure 4 on the zeta potential of NPs produced with both methodologies under different pH values. -Figure 5: Data corresponding to manuscript Figure 5 on the drug release profiles from NPs elaborated with both methodologies. -Figure 6: Data corresponding to manuscript Figure 6 on the cytotoxic effect on MCF-7 human breast adenocarcinoma cells of free gemcitabine, blank and gemcitabine-loaded NPs produced with both methodologies.application/vnd.ms-excelengAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Antitumor drugDouble emulsion/solvent evaporationFlow Focusing®Gemcitabine NanoparticlesPoly(dl-lactide-co-glycolide)AntitumoralDoble-emulsión/evaporación de solventeNanopartículas de Gemcitabinaácido poli(dl-láctico-co-glicólico)info:eu-repo/semantics/datasetinfo:eu-repo/semantics/openAccess10.12795/11441/167588