Santana Garrido, ÁlvaroDurán Lobato, María MatildeMate Barrero, AlfonsoMartín Banderas, LucíaVázquez Cueto, Carmen María2025-01-092025-01-092021-022024Santana Garrido, Á., Durán Lobato, M.M.,...,Vázquez Cueto, C.M. (2024). Dataset from Ophthalmic wild olive (ACEBUCHE) oil nanoemulsions exert oculoprotective effects against oxidative stress induced by arterial hypertension. Int J Pharm. 2024, vol. 649, p. 123602.. idUS (Depósito de Investigación de la Universidad de Sevilla). https://doi.org/10.12795/11441/166300.https://hdl.handle.net/11441/166300Dataset of the publication ‘Ophthalmic wild olive (acebuche) oil nanoemulsions exert oculoprotective effects against oxidative stress induced by arterial hypertension'. The work was primarily funded by the state project PID2019-109002RB-I00. The data present the development of a formulation based on acebuchina (ACE) oil nanoemulsions and its beneficial properties on the cornea and retina of animals with arterial hypertension induced by L-NAME. The data generated were collected between 2021 and 2023.A single Excel file with each sheet collecting the data corresponding to a figure or table: -Table 2: data corresponding to manuscript Table 2 on the physicochemical characterization of the nanoemulsions (NEs) -Figure 3: data corresponding to manuscript Figure 3 displaying the rheological evaluation of the NEs -Figure 5A-B: data corresponding to manuscript Figure 5A-B displaying the corneal layer thickness measurements. -Figure 5C-D: data corresponding to manuscript Figure 5A-B displaying the retinal layer thickness measurements. -Figure 6: data corresponding to manuscript Figure 6 regarding reactive oxygen species (ROS) measured by DHE staining in the corneal layers. -Figure 7: data corresponding to manuscript Figure 7 regarding ROS measured by DHE staining in the retinal layers. -Figure 8A-B: data corresponding to manuscript Figure 8A-B regarding NADPH oxidase activity and ROS sources in cornea homogenates. -Figure 8C: data corresponding to manuscript Figure 8C displaying the corneal NOX isoform mRNA expression. -Figure 8D-E: data corresponding to manuscript Figure 8D-E regarding NADPH oxidase activity and ROS sources in retina homogenates. -Figure 8F: data corresponding to manuscript Figure 8F displaying the retinal NOX isoform mRNA expression.application/vnd.ms-excelengAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AcebucheCórneaEstrés oxidativoHipertensión arterialNanoemulsionesRetinaAcebuche oilCorneaL-NAME hypertensionNanoemulsionOxidative stressinfo:eu-repo/semantics/datasetinfo:eu-repo/semantics/openAccesshttps://doi.org/10.12795/11441/166300