2025-07-082025-07-082025-04-04Capelo Avilés, S., Fez Febré, M.d., Rodríguez Gómez, S., Cabezas Giménez, J., Oliveira, R.T.d., Gallo Stampino, I.I. y Galán Mascarós, J.R. (2025). Selective adsorption of CO2 in TAMOF-1 for the separation of CO2/CH4 gas mixtures. Nature Communications, 16 (1), 3243. https://doi.org/10.1038/s41467-025-58426-w.2041-1723https://hdl.handle.net/11441/175126TAMOF-1 is a robust, highly porous metal–organic framework built from Cu2+ centers linked by a L-histidine derivative. Thanks to its high porosity and homochirality, TAMOF-1 has shown interesting molecular recognition properties, being able to resolve racemic mixtures of small organic molecules in gas and liquid phases. Now, we have discovered that TAMOF-1 also offers a competitive performance as solid adsorbent for CO2 physisorption, offering promising CO2 adsorption capacity ( > 3.8 mmol g–1) and CO2/CH4 Ideal Adsorbed Solution Theory (IAST) selectivity ( > 40) at ambient conditions. Moreover, the material exhibits favorable adsorption kinetics under dynamic conditions, demonstrating good stability in high-humidity environments and minimal degradation in strongly acidic media. We have identified the key interactions of CO2 within the TAMOF-1 framework by a combination of structural (neutron diffraction), spectroscopic and theoretical analyses which conclude a dual-site adsorption mechanism with the majority of adsorbed CO2 molecules occupying the empty voids in the TAMOF-1 channels without strong, directional supramolecular interactions. This very weak dominant binding opens the possibility of a low energy regeneration process for convenient CO2 purification. These features identify TAMOF-1 as a viable solid-state adsorbent for the realization of affordable biogas upgrading.application/pdf15 p.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1038/s41467-025-58426-w