Conejo Gonzalo, Mª CarmenGarcía Luque, IsabelMartínez Martínez, LuisPicabea de la Peña, LeandroPascual Hernández, Álvaro2017-07-272017-07-272003-07-01Conejo Gonzalo, M.C., García Luque, I., Martínez Martínez, L., Picabea de la Peña, L. y Pascual Hernández, Á. (2003). Zinc eluted from siliconized latex urinary catheters decreases OprD expression, causing carbapenem resistance in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 47 (7), 2313-2315.0066-4804 (impreso)1098-6596 (electrónico)http://hdl.handle.net/11441/63346The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is responsible for this phenomenon. We have found that zinc exerts a negative effect on the expression of OprD, the porin responsible for carbapenem entry into P. aeruginosa.application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1128/AAC.47.7.2313-2315.2003