Turck, D.Cámara, M.Bohn, T.Castenmiller, J.de Henauw, S.Jos Gallego, Ángeles MencíaMaciuk, A.Mangelsdorf, I.McNulty, B.Naska, A.Hirsch-Ernst, K. I.EFSA Panel on Nutrition2025-08-072025-08-072025Turck, D., Cámara, M., Bohn, T., Castenmiller, J., de Henauw, S., Jos Gallego, Á.M.,...,EFSA Panel on Nutrition, (2025). Safety of D-allulose as a Novel Food Pursuant to Regulation (EU) 2015/2283. EFSA Journal, 26 (6), e9468.https://doi.org/10.2903%2Fj.efsa.2025.9468.1831-4732https://hdl.handle.net/11441/176088Following a request from the European Commission, the EFSA Panel on Nutrition,Novel Foods and Food Allergens (NDA) was asked to deliver an opinion onD-allulose as a novel food (NF) pursuant to Regulation (EU) 2015/2283. During therisk assessment, the Panel identified a number of data gaps, which needed to beaddressed by the applicant. Therefore, an EFSA request for additional informationwas sent to the applicant. The requested data concerned the identity, the produc-tion process, proposed uses and use levels, genotoxicity and human data of theNF. Despite being contacted several times, the applicant did not reply to EFSA'srequests for additional data. Based on the available data, the Panel concludes thatthe safety of the NF, i.e. D-allulose, cannot be established.application/pdf11 p.engAttribution-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nd/4.0/D-alluloseD-psicoseMonosaccharideNovel foodSugar substituteinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.2903%2Fj.efsa.2025.9468