Barreales Suárez, SofíaCallejón Mochón, ManuelAzoulay, StéphaneBello López, Miguel ÁngelFernández Torres, Rut2024-01-112024-01-112018Barreales Suárez, S., Callejón Mochón, M., Azoulay, S., Bello López, M.Á. y Fernández Torres, R. (2018). Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata. Science of the Total Environment, 622-623, 655-663. https://doi.org/10.1016/j.scitotenv.2017.11.244.0048-96971879-1026https://hdl.handle.net/11441/153250A procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass spectrometry (LC-QTOF/MS) was optimized and validated. Best results were obtained using microwave assisted extraction of 1.0 g of homogeneous lyophilized samples and 5 mL of a mixture ACN:H2O (1:1 v/v) as extracting solvent. Analytical recoveries ranged from 60 to 107% with relative standard deviation (RSD) lower than 15%. Limits of quantitation (LOQ) for the 6 pharmaceuticals flumequine (FLM), carbamazepine (CBZ), ciprofloxacin (CPR), enrofloxacin (ENR), diclofenac (DCL), and ibuprofen (IBU) were in the range 20.8–125 ng g− 1. The method was satisfactory applied for an uptake study in Lavandula dentata samples finding quantifying concentrations of FLM and CBZ in roots, leaf and stem.application/pdf26 p.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/JuncusLavandula dentataLiquid chromatography quadrupole time-of-flightMicrowave extractionPharmaceuticalsSalicorniainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1016/j.scitotenv.2017.11.244