Pérez García, PabloHuertas Sánchez, GloriaOlmo Fernández, AlbertoMaldonado-Jacobi, AndrésSerrano Viseas, Juan AlfonsoMartín Rubio, María EstherDaza Navarro, María PaulaYúfera García, AlbertoRueda Rueda, AdoraciónSánchez Aguayo, Inmaculada2018-09-072018-09-072018Pérez García, P., Huertas Sánchez, G., Olmo Fernández, A., Maldonado-Jacobi, A., Serrano Viseas, J.A., Martín Rubio, M.E.,...,Yúfera García, A. (2018). Remote Cell Growth Sensing Using Self-Sustained Bio-Oscillations. Sensor, 18 (8), 1-13.1424-8220https://hdl.handle.net/11441/78370A smart sensor system for cell culture real-time supervision is proposed, allowing for a significant reduction in human effort applied to this type of assay. The approach converts the cell culture under test into a suitable “biological” oscillator. The system enables the remote acquisition and management of the “biological” oscillation signals through a secure web interface. The indirectly observed biological properties are cell growth and cell number, which are straightforwardly related to the measured bio-oscillation signal parameters, i.e., frequency and amplitude. The sensor extracts the information without complex circuitry for acquisition and measurement, taking advantage of the microcontroller features. A discrete prototype for sensing and remote monitoring is presented along with the experimental results obtained from the performed measurements, achieving the expected performance and outcomes.application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Smart sensingBioimpedanceCell cultureOBTReal-time monitoringinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.3390/s18082550