2016-03-212016-03-2120099788461328369http://hdl.handle.net/11441/38864We consider spiking neural P systems as devices which can be used to perform some basic arithmetic operations, namely addition, subtraction, comparison and multiplication by a fixed factor. The input to these systems are natural numbers expressed in binary form, encoded as appropriate sequences of spikes. A single system accepts as inputs numbers of any size. The present work may be considered as a ¯rst step towards the design of a CPU based on the working of spiking neural P systems.application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccess