González Mauraza, Nuria HaideeLeón González, Antonio JoséEspartero Sánchez, José LuisGallego Fernández, Juan BautistaSánchez Hidalgo, MarinaMartín Cordero, Carmen2021-05-122021-05-122016González Mauraza, N.H., León González, A.J., Espartero Sánchez, J.L., Gallego Fernández, J.B., Sánchez Hidalgo, M. y Martín Cordero, C. (2016). Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp. Natural Product Communications, 11 (3), 405-406.1934-578X (impreso)1934-578X (electrónico)https://hdl.handle.net/11441/108935The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3-O-methyl-chiro-inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of R. monosperma, and its structure established on the basis of spectroscopic techniques (1D/2D NMR) and MS. Identification and quantification of pinitol in R. raetam and R. sphaerocarpa were also performed. R. monosperma had the highest concentration of pinitol (2.3%). The presence of pinitol in aqueous extracts of Retama spp. may explain the adaptation of these plants to drought and salinity. Furthermore, pinitol could be considered as a mediator in the anti-inflammatory and hypoglycemic activities of Retama spp., which are traditionally used to treat diabetes.application/pdf2 p.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/RetamaPinitolCyclitol3-O-Methyl-chiro-inositolinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1177/1934578X1601100321