Fonte, LuisAcosta, ArmandoSarmiento, María E.Norazmi, Mohd NorGinori, MaríaArmas, Yaxsier deCalderón Sandubete, Enrique José2023-07-042023-07-042022Fonte, L., Acosta, A., Sarmiento, M.E., Norazmi, M.N., Ginori, M., Armas, Y.d. y Calderón Sandubete, E.J. (2022). Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa. TROPICAL MEDICINE AND INFECTIOUS DISEASE, 7 (8), 157. https://doi.org/10.3390/tropicalmed7080157.2414-6366https://hdl.handle.net/11441/147696There is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection.application/pdf8 p.engAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Pulmonary fibrosisSub-Saharan AfricaPostacute COVID-19 syndromeTuberculosisHelminth coinfectioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.3390/tropicalmed7080157