2017-12-212017-12-212017Martín Bueno, J., Romero Gracia, A. y García Asuero, A. (2017). Fitting Nonlinear Calibration Curves: No Models Perfect. Journal of Analytical Sciences, Methods and Instrumentation, 7, 1-17.2164-2745 (impreso)http://hdl.handle.net/11441/67961The study of the calibration of a series of compounds of environmental concern (six perfluoroalkyl compounds (perfluorooctane sulfonic acid and five perfluoroalkyl carboxylic acids), three preservatives (methyl-, ethyl- and propylparabens) and the brominated flame retardant hexabromocyclododecane) by LC-MS/MS has been carries out, with a view to their simultaneous determination in samples of environmental interest. In some cases nonlinear calibration curves are obtained, but restricting the concentration range a linear model may be used to fit the data. Residual analysis has been performed in order to verify which models fit the data better, opting for a compromise decision given the apparent complexity of residuals plots. As Box states there are no perfect models (but models that work better than others).application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/CalibrationNon Linear CalibrationResidual AnalysisLiquid Chromatography - Tandem Mass SpectrometryEmerging Pollutantsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.4236/jasmi.2017.71001