2021-04-202021-04-202021Ruiz Martínez, F.J., Arjona Valladares, A. y Gómez González, C.M. (2021). Mismatch Negativity and Stimulus-Preceding Negativity in Paradigms of Increasing Auditory Complexity: A Possible Role in Predictive Coding. Entropy, 23 (3), Article 346.1099-4300 (electrónico)https://hdl.handle.net/11441/107484The auditory mismatch negativity (MMN) has been considered a preattentive index of auditory processing and/or a signature of prediction error computation. This study tries to demonstrate the presence of an MMN to deviant trials included in complex auditory stimuli sequences, and its possible relationship to predictive coding. Additionally, the transfer of information between trials is expected to be represented by stimulus-preceding negativity (SPN), which would possibly fit the predictive coding framework. To accomplish these objectives, the EEG of 31 subjects was recorded during an auditory paradigm in which trials composed of stimulus sequences with increasing or decreasing frequencies were intermingled with deviant trials presenting an unexpected ending. Our results showed the presence of an MMN in response to deviant trials. An SPN appeared during the intertrial interval and its amplitude was reduced in response to deviant trials. The presence of an MMN in complex sequences of sounds and the generation of an SPN component, with different amplitudes in deviant and standard trials, would support the predictive coding framework.application/pdf15 p.engMismatch negativityStimulus preceding negativityContingent negative variationPredictive codingRegularity-violation hypothesisIntertrial intervalinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccess10.3390/e23030346