Cueto López, Marina deRodríguez Martínez, José ManuelSoriano Pérez, Manuel JesúsLópez Cerero, LorenaVenero Recio, José LuisPascual Hernández, Álvaro2017-07-272017-07-272008Cueto López, M., Rodríguez Martínez, J.M., Soriano Pérez, M.J., López Cerero, L., Venero, J. y Pascual Hernández, Á. (2008). Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation. Journal of Clinical Microbiology, 46 (4), 1558-1560.0095-1137 (impreso)1098-660X (electronico)http://hdl.handle.net/11441/63345The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with a preexisting parC mutation is reported. Failure was due to the emergence of a gyrA mutation after 4 days of therapy. Problems encountered in detecting first-step mutation isolates are discussed.application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1128/JCM.02066-07