Fernández de Cañete Rodríguez, Francisco JavierLuque Rodríguez, JoaquínBarbancho Concejero, JulioMuñoz Martínez, Víctor Fernando2019-10-252019-10-252014Fernández de Cañete Rodríguez, F.J., Luque Rodríguez, J., Barbancho Concejero, J. y Muñoz Martínez, V.F. (2014). Modelling of long-term and short-term mechanisms of arterial pressure control in the cardiovascular system: An object-oriented approach. Computers in Biology and Medicine, 47 (April 2014), 104-112.0010-4825https://hdl.handle.net/11441/89898A mathematical model that provides an overall description of both the short- and long-term mechanisms of arterial pressure regulation is presented. Short-term control is exerted through the baroreceptor reflex while renal elimination plays a role in long-term control. Both mechanisms operate in an integrated way over the compartmental model of the cardiovascular system. The whole system was modelled in MODELICA, which uses a hierarchical object-oriented modelling strategy, under the DYMOLA simulation environment. The performance of the controlled system was analysed by simulation in light of the existing hypothesis and validation tests previously performed with physiological data, demonstrating the effectiveness of both regulation mechanisms under physiological and pathological conditions.application/pdfengAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Object-oriented modellingCardiovascular systemPressure controlMODELICA programming languageDYMOLA simulation environmentinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1016/j.compbiomed.2014.01.006