Calderón Cabrera, CristinaMontero, I.Morales, R. M.Sánchez, J.Carrillo, E.Caballero Velázquez, TeresaPrats, C.Bernal, R.De Blas, J. M.Pérez Simón, José Antonio2022-02-092022-02-092013Calderón Cabrera, C., Montero, I., Morales, R.M., Sánchez, J., Carrillo, E., Caballero Velázquez, T.,...,Pérez Simón, J.A. (2013). Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis. Leukemia Research Reports, 2 (2), 79-81.2213-0489https://hdl.handle.net/11441/129806Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase and increases to 40–70% in advanced disease. Progression of CML from chronic phase to accelerated phase or blast crisis is often associated with secondary chromosomal aberrations. We report an exceptional case of CML as debut in lymphoblastic blast crisis and a subsequent progression in myeloblastic blast crisis with rare cytogenetic abnormalities.application/pdf3engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Chromosomal abnormalitiesChronic myeloid leukemia (CML)Cytogenetic abnormalitiesChromosomal aberrationsLymphoblastic blast crisisMyeloblastic blast crisisinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1016/j.lrr.2013.08.001