Jimeno González, SoniaPrados Carvajal, RosarioHuertas Sánchez, Pablo2025-01-142025-01-142019Jimeno González, S., Prados Carvajal, R. y Huertas Sánchez, P. (2019). The Role of RNA and RNA-related Proteins in the Regulation of DNA Double Strand Break Repair Pathway Choice. DNA Repair, 81, 102662. https://doi.org/10.1016/j.dnarep.2019.102662.1568-78641568-7856https://hdl.handle.net/11441/166621DNA end resection is a critical step in the repair of DNA double strand breaks. It controls the way the lesion is going to be repaired, thus its regulation has a great importance in maintaining genomic stability. In this review, we focus in recent discoveries in the field that point to a modulation of resection by RNA molecules and RNA-related proteins. Moreover, we aim to reconcile contradictory reports on the positive or negative effect of DNA:RNA hybrids in the resection process.application/pdf19 p.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/DNA double strand break repairHomologous recombinationNHEJR-loopsRNAinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccesshttps://doi.org/10.1016/j.dnarep.2019.102662