dc.creator | Romero Gómez, Manuel | es |
dc.creator | Ontanilla-Clavijo, Guillermo | es |
dc.creator | Ampuero Herrojo, Javier | es |
dc.creator | Borreguero, Samuel | es |
dc.creator | Rosell, Javier | es |
dc.date.accessioned | 2019-06-27T18:04:00Z | |
dc.date.available | 2019-06-27T18:04:00Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Romero Gómez, M., Ontanilla-Clavijo, G., Ampuero Herrojo, J., Borreguero, S. y Rosell, J. (2019). Usefulness of bioelectrical impedance analysis for monitoring patients with refractory ascites. Revista Española de Enfermedades Digestivas, 111 (3), 223-227. | |
dc.identifier.issn | 1130-0108 | es |
dc.identifier.uri | https://hdl.handle.net/11441/87654 | |
dc.description.abstract | Background: bioelectrical impedance analysis is a technique for the determination of the hydropic component. The hydropic component, determined by blood volume, could
be a reflection of the hemodynamic situation. This study
aimed to evaluate the usefulness of peripheral bioelectrical
impedance analysis (BIA) for the prediction of hemodynamic changes in large-volume paracentesis and prognosis.
Methods: this was a proof-of-concept prospective study of
14 patients with liver cirrhosis and refractory ascites. Peripheral bioimpedance was measured three times using a
portable device, IVOL®, before and after large-volume paracentesis, at different frequencies (5, 10, 20, 50, 100 and 200 kHz). Consequently, resistance, reactance and phase angle were obtained, both pre- and post-paracentesis (the difference between them was defined as Δ).
Results: the mean age of patients was 62.2 ± 9.6 years, the
Child-Pugh was 8.4 ± 1.3 and the MELD score was 15.2 ± 3.9. A direct correlation between the extraction of ascitic fluid
and Δresistance (10 kHz [r = 0.722; n = 12; p = 0.008], 20 kHz [r = 0.658; n = 12; p = 0.020] and 50 kHz [r = 0.519; n = 14; p = 0.057]) was observed. The presence of edema was related to lower values of both pre-paracentesis resistance (10 Hz [23.9 ± 8 vs 32.2 ± 4; p = 0.043]) and phase angle (5 kHz [-1.9 ± 2.8 vs 5.9 ± 7.3; p = 0.032]). Pre-paracentesis phase angle was directly correlated with the decline in blood pressure after paracentesis at lower frequencies (5 kHz [r = 0.694; n = 13; p = 0.008] and 10 kHz [r = 0.661; n = 13; p = 0.014]). Lower frequencies of Δphase-angle impacted on patient prognosis (5 kHz [-8.6 ± 5 vs -2.5 ± 2.7; p = 0.021]), patients with Δphase-angle 5 kHz > -4 had a higher rate of mortality (83.3% [5/6] vs 0% [0/6]; logRank 7.306, p = 0.007). Δresistance values were associated with overt HE at six months (10 kHz [4.9 ± 2.5 vs -0.4 ± 4.7; p = 0.046]).
Conclusions: in conclusion, a significant correlation between peripheral impedance and hemodynamic changes was found. Impedance was also significantly related to prognosis and overt hepatic encephalopathy. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Sociedad Española de Patología Digestiva | es |
dc.relation.ispartof | Revista Española de Enfermedades Digestivas, 111 (3), 223-227. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Cirrhosis | es |
dc.subject | Refractory ascites | es |
dc.subject | Bioelectrical analysis | es |
dc.subject | Bioimpedance | es |
dc.subject | Paracentesis | es |
dc.title | Usefulness of bioelectrical impedance analysis for monitoring patients with refractory ascites | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.identifier.doi | 10.17235/reed.2018.5634/2018 | es |
dc.contributor.group | Universidad de Sevilla. CTS-532: Unidad de Hepatologia | es |
idus.format.extent | 5 | es |
dc.journaltitle | Revista Española de Enfermedades Digestivas | es |
dc.journaltitle | Revista Española de Enfermedades Digestivas | es |
dc.publication.volumen | 111 | es |
dc.publication.issue | 3 | es |
dc.publication.initialPage | 223 | es |
dc.publication.endPage | 227 | es |