Article
Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers
Author/s | Gallego Yerga, Laura
Lomazzi, Michela Sansone, Francesco Ortiz Mellet, Carmen Casnati, Alessandro García Fernández, José Manuel |
Department | Universidad de Sevilla. Departamento de Química Orgánica |
Publication Date | 2014 |
Deposit Date | 2018-09-25 |
Published in |
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Abstract | Stable core–shell nanospheres self-assemble in water from heterodimers combining a hydrophobic calix[4]arene moiety and a hydrophilic β-cyclodextrin head; their potential to encapsulate and provide sustained release of the ... Stable core–shell nanospheres self-assemble in water from heterodimers combining a hydrophobic calix[4]arene moiety and a hydrophilic β-cyclodextrin head; their potential to encapsulate and provide sustained release of the anticancer drug docetaxel and undergo surface post-modification with glycoligands targeting the macrophage mannose receptor is discussed. |
Citation | Gallego Yerga, L., Lomazzi, M., Sansone, F., Ortiz Mellet, C., Casnati, A. y García Fernández, J.M. (2014). Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers. Chemical Communications, 50, 7440-7443. |
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