Buscar
Mostrando ítems 11-20 de 141
Capítulo de Libro
A pathophysiological view of the neural stem cell niche
(Nova Science Publishers, INC. U.S., 2011)
Neural stem cells were described in the nervous system some decades ago as being responsible for adult neurogenesis and hence the structural plasticity in the tissue. These cells reside in specialized niches where they are ...
Artículo
Dnmt3b knock-down in enteric precursors reveals a possible mechanism by which this de novo methyltransferase is involved in the enteric nervous system development and the onset of Hirschsprung disease
(Impact Journals, 2017)
Hirschsprung disease (HSCR, OMIM 142623) is a pathology that shows a lack of enteric ganglia along of the distal gastrointestinal tract. This aganglionosis is attributed to an abnormal proliferation, migration, differentiation ...
Artículo
Prenatal Diagnosis of a Fetus with Congenital Heart Defect and Ring Chromosome 14
(Hindawi Publishing Corporation, 2012)
Monosomy of chromosome 14 has been reported in only a few prenatal cases. Generally, this monosomy is associated with a mosaicism of ring chromosome 14. Ring chromosome 14 is a rare cytogenetic entity with clinical ...
Artículo
HIF-2a is essential for carotid body development and function
(eLife Sciences Publications, 2018-04-19)
Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations facilitated by the sympathetic nervous system and carotid body (CB). Interactions between differing ...
Artículo
HIV-Infected Subjects With Poor CD4 T-Cell Recovery Despite Effective Therapy Express High Levels of OX40 and α4β7 on CD4 T-Cells Prior Therapy Initiation
(International Union of Immunological Societies, 2018-07-18)
Background HIV-infected subjects with suboptimal CD4 restoration despite suppressive combined antiretroviral treatment (cART) (immunodiscordant subjects) have been classically characterized after a variable period of time ...
Artículo
The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
(Company of Biologists Limited, 2015-01)
Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and clinical scenarios. Accordingly, hyperglycaemia has been shown to downregulate the expression of elements ...
Artículo
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan- Neuronal Activation in the Female Mouse.
(2016-10-14)
Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival and protect them from degeneration. The glial cell line-derived neurotrophic factor (GDNF) is believed ...
Artículo
Prenatal management and perinatal outcome in giant placental chorioangioma complicated with hydrops fetalis, fetal anemia and maternal mirror syndrome
(BioMed Central, 2012-07-28)
Background: Giant placental chorioangiomas have been associated with a number of severe fetal complications and high perinatal mortality. Case presentation: We report a case of giant chorioangioma with fetal hydrops, ...
Artículo
The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)
Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion of T cells with suppressive properties. In the current study, we analyzed the potential synergistic ...