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Artículo
Histone Mutants Separate R Loop Formation from Genome Instability Induction
(Elsevier, 2017)
R loops have positive physiological roles, but they can also be deleterious by causing genome instability, and the mechanisms for this are unknown. Here we identified yeast histone H3 and H4 mutations that facilitate R ...
Artículo
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
(Shared Science Publishers OG, 2019)
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular ...