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Artículo
Nuclear Envelope Integrity in Health and Disease: Consequences on Genome Instability and Inflammation
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The dynamic nature of the nuclear envelope (NE) is often underestimated. The NE protects, regulates, and organizes the eukaryote genome and adapts to epigenetic changes and to its environment. The NE morphology is characterized ...
Artículo
Molecular modelling of islet β-cell adaptation to inflammation in pregnancy and gestational diabetes mellitus
(Multidisciplinary Digital Publishing Institute (MDPI), 2019)
Gestational diabetes mellitus (GDM), a metabolic disease that develops with the increase in insulin resistance during late pregnancy, is currently one of the most common complications affecting pregnancy. The polygenic ...