Now showing items 1-4 of 4
Regulation of replication fork advance and stability by nucleosome assembly
(Multidisciplinary Digital Publishing Institute (MDPI), 2017)
he advance of replication forks to duplicate chromosomes in dividing cells requires the disassembly of nucleosomes ahead of the fork and the rapid assembly of parental and de novo histones at the newly synthesized strands ...
SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination
Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be ...
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
(Cold Spring Harbor Laboratory Press, 2016)
Mph1 is a member of the conserved FANCM family of DNA motor proteins that play key roles in genome maintenance processes underlying Fanconi anemia, a cancer predisposition syndrome in humans. Here, we identify Mte1 as a ...
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
(Shared Science Publishers OG, 2019)
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular ...