Now showing items 1-3 of 3
Repurposing of the tamoxifen metabolites to combat infections by multidrug-resistant gram-negative bacilli
(Multidisciplinary Digital Publishing Institute, 2021-03-22)
The development of new strategic antimicrobial therapeutic approaches, such as drug repurposing, has become an urgent need. Previously, we reported that tamoxifen presents therapeutic efficacy against multidrug-resistant ...
Efficacy of lysophosphatidylcholine as direct treatment in combination with colistin against acinetobacter baumannii in murine severe infections models
The stimulation of the immune response to prevent the progression of an infection may be an adjuvant to antimicrobial treatment. Here, we aimed to evaluate the efficacy of lysophosphatidylcholine (LPC) treatment in combination ...
Potential tamoxifen repurposing to combat infections by multidrug-resistant Gram-negative bacilli
The development of new strategic therapies for multidrug-resistant bacteria, like the use of non-antimicrobial approaches and/or drugs repurposed to be used as monotherapies or in combination with clinically relevant ...