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Article

Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study
(Elsevier, 2021)
Background The clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine whether clinical phenotypes of patients with COVID-19 can be derived from clinical data, to assess ...
Article

Temporal trends in hospitalizations due to diabetes complications during COVID-19 pandemic in Andalusia, Spain
(BMJ PUBLISHING GROUP, 2022)
Article

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients
(BMC, 2021-09-13)
Background Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three ...
Article

Impact of early interferon-β treatment on the prognosis of patients with COVID-19 in the first wave: A post hoc analysis from a multicenter cohort
(Elsevier France - Editions scientifiques medicales Elsevier, 2022)
Background: Interferon-β is an attractive drug for repurposing and use in the treatment of COVID-19, based on its in vitro antiviral activity and the encouraging results from clinical trials. The aim of this study was ...
Article

Prediction Accuracy of Serial Lung Ultrasound in COVID-19 Hospitalized Patients (Pred-Echovid Study)
(MDPI, 2021-10-20)
The value of serial lung ultrasound (LUS) in patients with COVID-19 is not well defined. In this multicenter prospective observational study, we aimed to assess the prognostic accuracy of serial LUS in patients admitted ...
Article

Assessing the impact of COVID-19 on liver cancer management (CERO-19)
(Elsevier BV, 2021)
Background & Aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether ...
Article

COVID-19 in hospitalized HIV-positive and HIV-negative patients: a matched study
(Wiley, 2021)
Objectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the ...
Article

Co-infections and superinfections complicating COVID-19 in cancer patients: a multicentre, international study
(Science Direct, 2021-07-22)
Background: We aimed to describe the epidemiology, risk factors, and clinical outcomes of co-infections and superinfections in onco-hematological patients with COVID-19. Methods: International, multicentre cohort study of ...
Article

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01
(2021-09-02)
Background Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there has been increasing urgency to identify pathophysiological characteristics leading to severe clinical course in patients infected ...
Article

Anakinra versus Baricitinib: Different Strategies for Patients Hospitalized with COVID-19
(MDPI, 2021-09-06)
Background: Immunomodulatory drugs have been used in patients with severe COVID-19. The objective of this study was to evaluate the effects of two different strategies, based either on an interleukin-1 inhibitor, anakinra, ...