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Mostrando ítems 31-40 de 74
Artículo
Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)
We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with carotid body (CB) cell aggregates. Amelioration of their motor syndrome is a result of the trophic ...
Artículo
Bases neurobiológicas de la drogadicción
(Viguera, 2002)
Introduction. Drugs of abuse cause addiction, characterized by compulsive and out of control drug use. Several neurochemical and molecular changes take place in the brain during the first phase of drug use which lead to ...
Artículo
Selective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal Transplantation
(2005)
Glial cell line-derived neurotrophic factor (GDNF) exerts a notable protective effect on dopaminergic neurons in rodent and primate models of Parkinson’s disease (PD). The clinical applicability of this therapy is, however, ...
Artículo
Dopamine induces intracellular Ca2+ signals mediated by alpha(1B)-adrenoceptors in rat pineal cells
(ELSEVIER SCIENCE BV, 2001)
We have studied the functional interaction of dopamine with a -adrenoceptor subtypes by measuring intracellular Ca2q 1 levels in pineal cells, a cell type where adrenoceptors are well characterized. We show that dopamine ...
Tesis Doctoral
Monitorización de la función sináptica normal y patológica en modelos animales
(2009-04-17)
El objetivo principal de esta Tesis Doctoral ha sido el estudio de la transmisión sináptica en la unión neuromuscular. El abordaje que hemos llevado a cabo ha sido triple: - BLOQUE 1: Estudio de la transmisión sináptica ...
Artículo
Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)
Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. It is characterized by lower motor neuron degeneration, progressive muscle paralysis and respiratory ...
Artículo
Tesis Doctoral
Enfermedad de parkinson y síntomas urinarios: estudio clínico y en modelos animales
(2008-06-24)
Los pacientes con Enfermedad de Parkinson (EP) presentan un mayor porcentaje de síntomas urinarios e incontinencia que la población general de su misma edad. Esta mayor frecuencia de síntomas urinarios es secundaria a ...
Tesis Doctoral