Browsing Artículos (Citología e Histología Normal y Patológica) by Funding agency "Instituto de Salud Carlos III"
Now showing items 1-8 of 8
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Article
A Quantitative Digital Analysis of Tissue Immune Components Reveals an Immunosuppressive and Anergic Immune Response with Relevant Prognostic Significance in Glioblastoma
(MDPI, 2022)Objectives: Immunostimulatory therapies using immune checkpoint blockers show clinical activity in a subset of glioblastoma ...
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Article
Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Systemic lupus erythematosus (SLE) is a chronic immune-inflammatory disease characterized by multiorgan affectation and ...
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Article
Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell–Matrix Interactions
(MDPI ; MDPI AG, 2022)Abstract: Endoglin (ENG) is a mesenchymal stem cell (MSC) marker typically expressed by active endothelium. This transmembrane ...
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Article
Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma
(Wiley, 2020)YAP1 and TAZ (WWTR1) oncoproteins are thefinal transducers of the Hippo tumor suppressor pathway. Deregula-tion of the ...
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Article
Histopathological Features of Pendred Syndrome Thyroids Align with Differences in the Expression of Thyroid‑Specific Markers, Apical Iodide Transporters, and Ciliogenesis Process
(HUMANA PRESS INC, 2022)Pendred syndrome (PDS) is an autosomal recessive disorder caused by mutations in the gene that encodes pendrin. Pendred ...
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Article
Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma
(Springer, 2022-10-11)The majority of current cancer therapies are aimed at reducing tumour growth, but there is lack of viable pharmacological ...
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Pdx1 Is Transcriptionally Regulated by EGR-1 during Nitric Oxide-Induced Endoderm Differentiation of Mouse Embryonic Stem Cells
(MDPI AG, 2022)The transcription factor, early growth response-1 (EGR-1), is involved in the regulation of cell differentiation, ...
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Article
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer
(Nature Research, 2021-09-16)Chromosomal instability (CIN) is a hallmark of cancer1. Yet, many childhood cancers, such as Ewing sarcoma (EwS), feature ...