Now showing items 1-3 of 3
Reformulating Pro-Oxidant Microglia in Neurodegeneration
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered ...
TET2 Regulates the Neuroinflammatory Response in Microglia
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for microglia in neuroinflammation and neurodegeneration, little is known about their epigenomic ...
Brainiac Caspases: Beyond the Wall of Apoptosis
(Frontiers Media, 2019)
For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions. In this mini review, ...