Now showing items 1-3 of 3
Caspase-8 inhibition represses initial human monocyte activation in septic shock model [Article]
(Impact Journals, 2016)
In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic potential of directly targeting innate immune cell activation to limit the cytokine storm and downstream ...
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex [Article]
(Society for Neuroscience, 2006)
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because sensitivity to inflammation is not equal in all brain structures, a direct relationship is not clear. ...
Reformulating Pro-Oxidant Microglia in Neurodegeneration [Article]
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered ...