Search
Now showing items 1-4 of 4
The role of Galectin-3 in α-synuclein-induced microglial activation [Article]
(BioMed Central, 2014)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology is characterized by intraneuronal protein aggregates of α -synuclein and progressive degeneration of ...
Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation [Article]
(BioMed Central, 2014)
Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and is accompanied by an inflammatory reaction that is believed to contribute to its pathogenesis. ...
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke [Article]
(BioMed Central, 2016)
Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells including resident microglia and infiltrating peripheral macrophages, which contribute to an ...
Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology [Article]
(Frontiers Media Research Foundation, 2018-11-14)
Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease (AD). Microglial response in AD has been principally studied in relation to amyloid-beta pathology ...