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AuthorVitorica Ferrández, Francisco Javier (3)Vizuete Chacón, María Luisa (3)Espinosa Oliva, Ana María (2)Jiménez Muñoz, Sebastián (2)Martínez de Pablos, Rocío (2)Muñoz Castro, Clara (2)Navarro Garrido, Victoria (2)Romero Molina, Carmen (2)Ruano Caballero, Diego (2)Sánchez Mico, María (2)... View MoreSubject
Inflammation (7)
Microglia (3)Neurodegeneration (2)Aging (1)Alzheimer Disease (1)Alzheimer’s disease (1)Autophagy (1)Caspases (1)Cell stress and aging (1)Dementia (1)... View MoreDate Issued2021 (3)2011 (1)2014 (1)2018 (1)2020 (1)Funding agencyInstituto de Salud Carlos III (1)Instituto de Salud Carlos III PI18/01556, PI18/01557 (1)Junta de Andalucía (1)Universidad de Sevilla US-1265062, US-1264806 (1)
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Article
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Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density 

Pintado Losa, Cristina; Revilla Torres, María Elisa; Vizuete Chacón, María Luisa; García Cuervo, Luisa; Vitorica Ferrández, Francisco Javier; Ruano Caballero, Diego; Castaño Navarro, Angélica (Elsevier, 2011)
To elucidate whether density of cells could contribute to the extent of microglial activation, we performed in vitro assays using three different densities of N13 microglia stimulated with LPS. Our results showed that ...
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Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology 

Romero Molina, Carmen; Navarro Garrido, Victoria; Sánchez Varo, Raquel María; Jiménez Muñoz, Sebastián; Fernández Valenzuela, Juan José; Sánchez Mico, María; Muñoz Castro, Clara; Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier; Vizuete Chacón, María Luisa (Frontiers Media Research Foundation, 2018-11-14)
Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease (AD). Microglial response in AD has been principally studied in relation to amyloid-beta pathology ...
Article
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Microglia: Agents of the CNS Pro-Inflammatory Response 

Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have ...
Article
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Proteostasis Dysfunction in Aged Mammalian Cells. The Stressful Role of Inflammation 

Ruano Caballero, Diego (Frontiers Media S.A., 2021)
Aging is a biological and multifactorial process characterized by a progressive and irreversible deterioration of the physiological functions leading to a progressive increase in morbidity. In the next decades, the world ...
Article
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Should we open fire on microglia? Depletion models as tools to elucidate microglial role in health and alzheimer’s disease 

Romero Molina, Carmen; Navarro Garrido, Victoria; Jiménez Muñoz, Sebastián; Muñoz Castro, Clara; Sánchez Mico, María; Gutiérrez, Antonia; Vitorica Ferrández, Francisco Javier; Vizuete Chacón, María Luisa (Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Microglia play a critical role in both homeostasis and disease, displaying a wide variety in terms of density, functional markers and transcriptomic profiles along the different brain regions as well as under injury or ...
Article
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Stress and inflammation: a detrimental combination in the development of neurodegenerative disease 

Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Venero Recio, José Luis (Smart Science and Technology, 2014)
Chronic stress accelerates the appearance of some neurodegenerative disorders, such as Alzheimer’s disease and Parkinson´s disease. On this review we firstly, describe some human epidemiological studies that highlight the ...
Article
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Editorial: Neurodegeneration: From Genetics to Molecules (Part II) 

Carvajal, karla Guadalupe; Martínez de Pablos, Rocío; Campos Peña, Victoria (Frontiers Media, 2021)
Among non-transmissible chronic diseases, neurodegenerative complications have become a big challenge in public health. Elongation of human lifespan, due in part to better health services, lifestyle changes, and improvements ...
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