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Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL
(MDPI, 2021-10-20)
3-Poly-phosphoinositides (PIP3) regulate cell survival, division, and migration. Both PI3-kinase (phosphoinositide-3-kinase) and PTEN (phosphatase and tensin-homolog in chromosome 10) control PIP3 levels, but the mechanisms ...