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Listar Artículos (Microbiología) por autor "Japón Rodríguez, Miguel Ángel"
Mostrando ítems 1-4 de 4
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Artículo
Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer
Galindo Moreno, María; Giráldez Macías, Servando; Sáez, Carmen; Japón Rodríguez, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (Nature Publishing Group, 2017)Cyclin-dependent kinase 1 (CDK1) is the central mammalian regulator of cell proliferation and a promising therapeutic ...
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Artículo
Glycogen Synthase Kinase-3-ß (GSK3ß) negatively regulates PTTG1/human Securin protein stability, and GSK3ß inactivation correlates with securin accumulation in breast tumors.
Mora Santos, María del Mar; Limón Mortés, María Cristina; Giráldez Macías, Servando; Herrero Ruiz, Joaquín; Sáez, Carmen; Japón Rodríguez, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (The American Society for Biochemistry and Molecular Biology, 2011)PTTG1, also known as securin, is an inactivating partner of separase, the major effector for chromosome segregation during ...
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Artículo
Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells
Jiménez Guerrero, Rocío; Gasca Bellido, Jessica María; Flores, M. Luz; Pérez Valderrama, Begoña; Medina López, Rafael; Tortolero García, María Dolores; Romero Portillo, Francisco; Japón Rodríguez, Miguel Ángel (MDPI, 2018)Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and ...
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Artículo
βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy
Herrero Ruiz, Joaquín; Mora Santos, María del Mar; Giraldez Macias, Servando; Sáez Torres, Carmen; Romero Portillo, Francisco; Japón Rodríguez, Miguel Ángel (Impact Journals, 2014)n mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the ...