Search
Now showing items 1-10 of 126
PhD Thesis
Penetración y actividad intracelular de cinco fluorquinolonas en leucocitos polimorfonucleares humanos
(1994)
La finalidad de este estudio ha sido determinar la capacidad de un grupo de quinolonas; fluorquinolonas, de penetrar en el interior de los leucocitos polimorfonucleares humanos, estudiar los mecanismos involucrados en dicha ...
Article
Enhanced antibacterial activity of repurposed mitomycin C and imipenem in combination with the lytic phage vB_KpnMVAC13 against clinical isolates of klebsiella pneumoniae
(American Society Microbiology, 2021)
Klebsiella pneumoniae is an opportunistic Gram-negative pathogen that employs different strategies (resistance and persistence) to counteract antibiotic treatments. This study aimed to search for new means of combatting ...
Article
OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014-2015
(Oxford University Press, 2019)
The aim of this study was to characterize the population structure of 56 OXA-48-like-producing Klebsiella pneumoniae isolates, as well as extended-spectrum β-lactamase (ESBL) and carbapenemase genes, recovered in 2014 and ...
Article
Impact of the MIC of Piperacillin-Tazobactam on the Outcome of Patients with Bacteremia Due to Extended-Spectrum-B-Lactamase- Producing Escherichia coli
(American Society for Microbiology, 2013-07)
We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39 bloodstream infections due to extended- spectrum-B-lactamase-producing Escherichia coli. All 11 patients with urinary tract infections ...
Article
Efficacy of β-lactam/β-lactamase inhibitors to treat extended-spectrum beta-lactamase-producing Enterobacterales bacteremia secondary to urinary tract infection in kidney transplant recipients
(Willey-Blackwell, 2021)
Background Whether active therapy with β-lactam/β-lactamase inhibitors (BLBLI) is as affective as carbapenems for extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) bloodstream infection (BSI) secondary ...
PhD Thesis
Impacto de la concentración mínima inhibitoria (cmi) y de los puntos de corte clínicos (clsi y eucast) de las combinaciones betalactámicos / inhibidores de betalactamasas en el pronóstico de bacteriemias por enterobacteriaceae
(2017-09-27)
Los puntos de corte clínicos se utilizan para predecir la eficacia terapéutica de un antibiótico cuando se utiliza a la dosis estándar para el tratamiento de una infección causada por el patógeno analizado. Por lo tanto, ...
Article
In vitro activities of ketolide HMR 3647, macrolides, and clindamycin against coryneform bacteria
(American Society for Microbiology, 1998-12-01)
The in vitro activity of ketolide HMR 3647 against coryneform bacteria isolated from clinical samples was evaluated. Except against Corynebacterium jeikeium and C. urealyticum, HMR 3647 showed high activity against ...
Article
Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
In 2014–2015, the main CTX-M-15- and OXA-48-producing clone in our region was ST15. Recently, K. pneumoniae ST15 isolates co-producing VIM-1 and CTX-M-15 were detected in several hospitals. The aim was to study the emergence ...
Article
Epidemiological and Clinical Complexity of Amoxicillin-Clavulanate- Resistant Escherichia coli
(American Society for Microbiology, 2013-07)
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary ...
PhD Thesis
Bacteriemias por Escherichia coli productor de beta-lactamasas de espectro extendido epidemiología clínica y molecular
(2010)
Hasta hace poco las infecciones por Escherichia coli productor de BLEE eran infrecuentes, pero en los últimos años estamos asistiendo a un aumento en su frecuencia, por lo que estamos ante un fenómeno emergente no sólo en ...