Browsing Microbiología by Subject "apoptosis"
Now showing items 1-3 of 3
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Article
Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer
(Impact Journals, 2016)FBXW7 is a component of SCF (complex of SKP1, CUL1 and F-box-protein)-type ubiquitin ligases that targets several oncoproteins ...
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Article
Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells
(MDPI, 2018)Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and ...
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Article
βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy
(Impact Journals, 2014)n mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the ...