Now showing items 1-8 of 8

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      dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe 

      Rodrigues, Joana S.; Chenlo, Miguel; Bravo, Susana B.; Pérez Romero, Sihara; Suárez Fariña, María; Sobrino, Tomás; Sanz Pamplona, Rebeca; González Prieto, Román; Álvarez, Clara V. (Springer Nature, 2024-05-14)
      The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in ...
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      Fundamental physical cellular constraints drive self-organization of tissues 

      Sánchez Gutiérrez, Daniel; Tozluoglu, Melda; Barry, Joseph D.; Pascual, Alberto; Mao, Yanlan; Escudero Cuadrado, Luis María (Wiley-Blackwell, 2016)
      Morphogenesis is driven by small cell shape changes that modulate tissue organization. Apical surfaces of proliferating ...
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      Loss of GATA4 causes ectopic pancreas in the stomach 

      Rodríguez Seguel, Elisa del Pilar; Villamayor, Laura; Arroyo, Noelia; De Andrés, Mónica P.; Real, Francisco X.; Martín, Franz; Cano, David A.; Rojas, Anabel (John Wiley & Sons, 2020-04)
      Pancreatic heterotopia is defined as pancreatic tissue outside its normal location in the body and anatomically separated ...
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      Metabolic Reprogramming by Acly Inhibition Using SB-204990 Alters Glucoregulation and Modulates Molecular Mechanisms Associated with Aging 

      Sola García, Alejandro; Cáliz Molina, María Ángeles; Espadas, Isabel; Petr, Michael; Panadero Morón, Concepción; González Morán, Daniel; Martín Vázquez, María Eugenia; Narbona Pérez, Álvaro Jesús; López Noriega, Livia; Martínez Corrales, Guillermo; Martín Montalvo, Alejandro (Springer Nature, 2023)
      ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid ...
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      Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality 

      Mora Romero, Bella; Capelo Carrasco, Nicolás; Pérez Moreno, Juan José; Álvarez Vergara, María Isabel; Trujillo Estrada, Laura Isabel; Romero Molina, Carmen; Martínez Márquez, Emilio; Morano Catalan, Noelia; Vizuete Chacón, María Luisa; López Barneo, José; Nieto González, José Luis; García-Junco Clemente, Pablo; Vitorica Ferrández, Francisco Javier; Gutiérrez, Antonia; Macías, David; Rosales Nieves, Alicia E.; Pascual Bravo, Alberto (Nature, 2024-07-24)
      Primary mitochondrial diseases (PMDs) are associated with pediatric neurological disorders and are traditionally related ...
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      Non-productive angiogenesis disassembles Aß plaque-associated blood vessels 

      Álvarez Vergara, Maria I.; Rosales Nieves, Alicia E.; March Díaz, Rosana Rocío; Rodríguez Perinan, Guiomar; Lara Ureña, Nieves; Ortega de San Luis, Clara; Sánchez García, Manuel A.; Martín Bornez, Miguel; Gómez Gálvez, Pedro; Vicente Munuera, Pablo; Fernández Gómez, Beatriz; Marchena, Miguel Ángel (Springer Nature, 2021)
      The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature ...
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      NR5A2/LRH-1 Regulates the PTGS2-PGE2-PTGER1 Pathway Contributing to Pancreatic Islet Survival and Function 

      Martin Vázquez, Eugenia; Cobo Vuilleumier, Nadia; Araujo Legido, Raquel; Marín Cañas, Sandra; Nola, Emanuele; Dorronsoro, Akaitz; López Bermudo, Lucía; Crespo, Alejandra; Romero Zerbo, Silvana Y.; Comaills, Valentine; Gauthier, Benoit R. (Elsevier, 2022)
      LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets ...
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      The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection 

      Vicente Munuera, Pablo; Burgos Panadero, Rebeca; Noguera, Inmaculada; Navarro, Samuel; Noguera, Rosa; Escudero Cuadrado, Luis María (Wiley, 2020)
      Tumors are complex networks of constantly interacting elements: tumor cells, stromal cells, immune and stem cells, ...