Browsing Artículos (Biología Celular) by Funding agency "Instituto de Salud Carlos III"
Now showing items 1-8 of 8
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Article
dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe
(Springer Nature, 2024-05-14)The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in ...
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Article
Fundamental physical cellular constraints drive self-organization of tissues
(Wiley-Blackwell, 2016)Morphogenesis is driven by small cell shape changes that modulate tissue organization. Apical surfaces of proliferating ...
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Loss of GATA4 causes ectopic pancreas in the stomach
(John Wiley & Sons, 2020-04)Pancreatic heterotopia is defined as pancreatic tissue outside its normal location in the body and anatomically separated ...
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Metabolic Reprogramming by Acly Inhibition Using SB-204990 Alters Glucoregulation and Modulates Molecular Mechanisms Associated with Aging
(Springer Nature, 2023)ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid ...
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Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality
(Nature, 2024-07-24)Primary mitochondrial diseases (PMDs) are associated with pediatric neurological disorders and are traditionally related ...
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Article
Non-productive angiogenesis disassembles Aß plaque-associated blood vessels
(Springer Nature, 2021)The human Alzheimer’s disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature ...
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NR5A2/LRH-1 Regulates the PTGS2-PGE2-PTGER1 Pathway Contributing to Pancreatic Islet Survival and Function
(Elsevier, 2022)LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets ...
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The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection
(Wiley, 2020)Tumors are complex networks of constantly interacting elements: tumor cells, stromal cells, immune and stem cells, ...