Now showing items 11-16 of 16
ATM specifically mediates repair of double-strand breaks with blocked DNA ends [Article]
(Nature Publishing Group, 2014)
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator ...
Neuromuscular disease classification system [Article]
(Spie-soc photo-optical instrumentation engineers, 2013)
Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist specialist. A system for objective analysis and classification of muscular dystrophies and ...
Scutoids are a geometrical solution to three-dimensional packing of epithelia [Article]
(Nature Publishing Group, 2018)
As animals develop, tissue bending contributes to shape the organs into complex three-dimensional structures. However, the architecture and packing of curved epithelia remains largely unknown. Here we show by means of ...
Epithelial organisation revealed by a network of cellular contacts [Article]
(Nature Publishing Group, 2011)
The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. Understanding this process is limited by the lack of systematic characterization of epithelial organisation. ...