Browsing by Author "Wellinger, Ralf Erik"
Now showing items 1-20 of 21
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A new challenge for data analytics: transposons
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A new connection of mRNP biogenesis and export with transcription-coupled repair
(Oxford University Press, 2007)Although DNA repair is faster in the transcribed strand of active genes, little is known about the possible contribution ...
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Adaptive response of saccharomyces hosts to totiviridae L-A dsRNA viruses Is achieved through intrinsically balanced action of targeted transcription factors
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Totiviridae L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, ...
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An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination
(American Society for Microbiology, 2006)THO/TREX, a conserved eukaryotic protein complex, is a key player at the interface between transcription and mRNP metabolism. ...
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PhD Thesis
Identification and Characterization of Factors Involved in Sodium Selenite Toxicity
(2021-07-06)Selenium (Se) is an essential micronutrient in many organisms. Despite being essential for some organisms, the range between ...
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Impaired manganese metabolism causes mitotic misregulation
(American Society for Biochemistry and Molecular Biology, 2012)Manganese is an essential trace element, whose intracellular levels need to be carefully regulated. Mn2+ acts as a cofactor ...
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Manganese is a physiologically relevant TORC1 activator in yeast and mammals
(eLife Sciences Publications, 2022)The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human ...
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Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function
(American Society for Biochemistry and Molecular Biology, 2015)Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss ...
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Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Understanding which intracellular signaling pathways are activated by manganese stress is crucial to decipher how metal ...
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Non‐Canonical Replication Initiation: You’re Fired!
(MDPI, 2017)The division of prokaryotic and eukaryotic cells produces two cells that inherit a perfect copy of the genetic material ...
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Rad52-independent accumulation of joint circular minichromosomes during S phase in Saccharomyces cerevisiae
(2003)We investigated the formation of X-shaped molecules consisting of joint circular minichromosomes (joint molecules) in ...
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Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu–Sir4 interaction
(Oxford University Press, 2017)Ultraviolet light (UV) causes DNA damage that is removed by nucleotide excision repair (NER). UVinduced DNA lesions must ...
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Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex
(American Society for Microbiology, 2006)THO/TREX is a conserved, eukaryotic protein complex operating at the interface between transcription and messenger ...
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Role for RNA: DNA hybrids in origin-independent replication priming in a eukaryotic system
(National Academy of Sciences, 2015)DNA replication initiates at defined replication origins along eukaryotic chromosomes, ensuring complete genome duplication ...
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PhD Thesis
Studies on the effects of persistent RNA priming on DNA replication and genomic stability.
(2014-07-03)La replicación y la transcripción del ADN suceden al mismo tiempo y en la misma molécula de ADN de modo que su correcta ...
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Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks
(Elsevier (Cell Press): OAJ, 2019)Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms ...
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Surface modulation of single-walled carbon nanotubes for selective bacterial cell agglutination
(Dove Medical Press, 2019)Background: Bacterial resistance to antibiotics is one of the biggest challenges facing medicine today. Anti-adhesive ...
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The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto ...
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Yeast as a model system to study metabolic impact of selenium compounds
(Shared Science Publishers, 2015)Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces ...