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Browsing by Author "Salvador de Lara, Manuel"
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Article
Insights into metabolic osmoadaptation of the ectoines-producer bacterium Chromohalobacter salexigens through a high-quality genome scale metabolic model
Piubeli, Francine; Salvador de Lara, Manuel; Argandoña Bertrán, Montserrat; Nieto Gutiérrez, Joaquín José; Bernal, Vicente; Pastor, José M.; Cánovas, Manuel; Vargas Macías, Carmen (BioMed Central, 2018)Background The halophilic bacterium Chromohalobacter salexigens is a natural producer of ectoines, compatible solutes ...
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Article
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens
Salvador de Lara, Manuel; Argandoña Bertrán, Montserrat; Naranjo Fernández, Emilia; Piubeli, Francine; Nieto Gutiérrez, Joaquín José; Vargas Macías, Carmen (Frontiers Media, 2018)Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the ...
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Article
Role of central metabolism in the osmoadaptation of the halophilic bacterium chromohalobacter salexigens
Pastor, José M.; Bernal, Vicente; Salvador de Lara, Manuel; Argandoña Bertrán, Montserrat; Vargas Macías, Carmen; Csonka, Laszlo N.; Sevilla, Ángel; Iborra, José Luis; Nieto Gutiérrez, Joaquín José; Cánovas, Manuel (American Society for Biochemistry and Molecular Biology Inc., 2013)Bacterial osmoadaptation involves the cytoplasmic accumulation of compatible solutes to counteract extracellular osmolarity. ...
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Article
Role of Trehalose in Salinity and Temperature Tolerance in the Model Halophilic Bacterium Chromohalobacter salexigens
Nieto Gutiérrez, Joaquín José; Salvador de Lara, Manuel; Rodríguez de Moya Vera, Javier; Argandoña Bertrán, Montserrat; Iglesias Guerra, Fernando; Csonka, Laszlo N.; Reina Bueno, Mercedes; Vargas Macías, Carmen (2012) -
Article
Understanding the interplay of carbon and nitrogen supply for ectoines production and metabolic overflow in high density cultures of Chromohalobacter salexigens
Salar García, María J.; Bernal, Vicente; Pastor, José M.; Salvador de Lara, Manuel; Argandoña Bertrán, Montserrat; Nieto Gutiérrez, Joaquín José; Vargas Macías, Carmen (BioMed Central, 2017)Background The halophilic bacterium Chromohalobacter salexigens has been proposed as promising cell factory for the ...
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Patent. Invention
Uso de la ectoína o sus derivados como agentes antiinflamantorios y/o antioxidantes en enfermedades causadas por la formacion de agregados proteicos
Salvador de Lara, Manuel; García Valero, Rosa María; Argandoña Bertran, Montserrat; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Nieto Gutiérrez, Joaquín José; Vargas Macías, Carmen (Oficina Española de Patentes y Marcas (OEPM), 2017-07-06)Uso de la ectoína o sus derivados como agentes antiinflamatorios y/o antioxidantes en enfermedades causadas por la ...