Browsing by Author "Ruiz Pérez, José Francisco"
Now showing items 1-13 of 13
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A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
(Public Library of Science, 2017)Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
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A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis
(Oxford University Press, 2006)Human DNA polymerase mu (Polm) is a family X member that has terminal transferase activity but, in spite of a non-orthodox ...
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AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants
(Public Library of Science, 2011)Transcription of the switch (S) regions of immunoglobulin genes in B cells generates stable R-loops that are targeted by ...
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An End to a Means: How DNA-End Structure Shapes the Double-Strand Break Repair Process
(Frontiers Media, 2020)Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5'-phosphate, 3'-hydroxyl moieties at the ...
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Are there mutator polymerases?
(Hindawi Publishing Corporation, 2003)DNA polymerases are involved in different cellular events, including genome replication and DNA repair. In the last few ...
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Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe
(Oxford University Press, 2005)As predicted by the amino acid sequence, the purified protein coded by Schizosaccharomyces pombe SPAC2F7.06c is a DNA ...
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Chromosomal translocations caused by either Pol32-dependent or Pol32-independent triparental break-induced replication
(American Society for Microbiology, 2009)Double-strand breaks (DSBs) are harmful DNA lesions that can generate chromosomal rearrangements or chromosome losses if ...
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DNA polymerase λ, a novel DNA repair enzyme in human cells
(American Society for Biochemistry and Molecular Biology Inc., 2002)DNA polymerase lambda (pol λ) is a novel family X DNA polymerase that has been suggested to play a role in meiotic ...
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Polμ tumor variants decrease the efficiency and accuracy of NHEJ
(Oxford University Press, 2017)The non homologous end-joining (NHEJ) pathway of double-strand break (DSB) repair often requires DNA synthesis to fill the ...
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Regulation of human Polλ by ATM-mediated phosphorylation during Non-Homologous End Joining
(Elsevier, 2018)DNA double strand breaks (DSBs) trigger a variety of cellular signaling processes, collectively termed the DNA-damage ...
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