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Browsing by Author "Rodríguez Gil, Alfonso"
Now showing items 1-20 of 20
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Article
Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles
Martín Banderas, Lucía; González Prieto, Román; Rodríguez Gil, Alfonso; Fernández Arévalo, María Mercedes; Flores Mosquera, María; Chávez de Diego, Sebastián; Gañán-Calvo, Alfonso M. (2011)Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of ...
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Article
Broad Transcriptomic Impact of Sorafenib and Its Relation to the Antitumoral Properties in Liver Cancer Cells
Contreras Bernal, Laura; Rodríguez Gil, Alfonso; Muntané Relat, Jordi; Cruz Díaz, Jesús de la (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Hepatocellular carcinoma (HCC) is one of the most frequent and essentially incurable cancers in its advanced stages. The ...
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Article
Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib
Rodríguez Gil, Alfonso; Escamilla Gómez, Virginia; Nufer, Melanie; Andújar Sánchez, Félix; Lopes Ramos, Teresa; Bejarano García, José Antonio; Caballero Velázquez, Teresa; Villadiego Luque, Francisco Javier; Pérez Simón, José Antonio (Nature Publishing Group, 2022)Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as ...
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Article
Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease
Ramos, Teresa L.; García Guerrero, Estefanía; Caballero Velázquez, Teresa; Rodríguez Gil, Alfonso; Caracuel García, Rocío; Nufer, Melanie; Robles Frías, María José; Barbado González, Mª Victoria; Pérez Simón, José Antonio (Nature Publishing Group, 2021-09-23)In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation ...
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Article
Editorial: Regulatory T cells in graft versus host disease
Rodríguez Gil, Alfonso; Pérez Simón, José Antonio; Ritz, Jerome; Lacerda, João F.; Soares, Maria V.D. (Frontiers Media, 2023-02-20)Regulatory T cells (Tregs) are modulators of the immune system that play a key role in maintaining self-tolerance. Treg ...
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Article
Effect of Vitamin D on Graft-versus-Host Disease
Rodríguez Gil, Alfonso; Carrillo-Cruz, Estrella; Marrero-Cepeda, Cristina; Rodríguez, Guillermo; Pérez Simón, José Antonio (MDPI, 2022)The different cell subsets of the immune system express the vitamin D receptor (VDR). Through the VDR, vitamin D exerts ...
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Article
Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair
Gaillard, Hélène; Tous Rivera, Cristina; Botet, Javier; González Aguilera, Cristina; Quintero, María José; Viladevall, Laia; García Rubio, María Luisa; Rodríguez Gil, Alfonso; Marín, Antonio; Ariño, Joaquín; Revuelta, José Luis; Chávez de Diego, Sebastián; Aguilera López, Andrés (Public Library of Science, 2009)RNA polymerases frequently deal with a number of obstacles during transcription elongation that need to be removed for ...
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PhD Thesis
Genómica funcional de la elongación transcripcional
Rodríguez Gil, Alfonso (2008)Los principales objetivos de esta Tesis Doctoral son: Desarrollo de un nuevo método para el estudio de la distribución ...
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PhD Thesis
Linfocitos T reguladores para pacientes con enfermedad injerto contra receptor crónica que no obtienen remisión completa con ruxolitinib
Escamilla Gómez, Virginia (2022-07-06) -
Presentation
One-step production of fluorescent encoded polystyrene microparticles using flow focusing. Potencial applicatios in high-throughput screening
Martín Banderas, Lucía; Flores Mosquera, María; Rodríguez Gil, Alfonso; Cebolla, Ángel; Chávez, S.; Gañán-Calvo, Alfonso M. (2005) -
Article
Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae
Ramos Sáenz, Ana; González Álvarez, Daniel; Rodríguez Galán, Olga; Rodríguez Gil, Alfonso; Gaspar, Sonia G.; Villalobo Polo, Eduardo; Dosil, Mercedes; Cruz Díaz, Jesús de la (Cold Spring Harbor Laboratory Press, 2019)In Saccharomyces cerevisiae, more than 250 trans-acting factors are involved in the maturation of 40S and 60S ribosomal ...
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Patent. Invention
Procedimiento y dispositivo para la obtención de partículas de tamaño micro y nanométrico
Gañán-Calvo, Alfonso M.; Martín Banderas, Lucía; Flores Mosquera, María; Rodríguez Gil, Alfonso; Chávez de Diego, Sebastián; Cebolla Ramírez, Ángel (Oficina Española de Patentes y Marcas (OEPM), 2007-06-14)Procedimiento y dispositivo para la obtención de partículas de tamaño micro y nanométrico. La presente invención está ...
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Article
Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation
Dehé, Pierre Marie; Dichtl, Bernhard; Schaft, Daniel; Roguev, Assen; Pamblanco, Mercè; Lebrun, Régine; Rodríguez Gil, Alfonso; Mkandawire, Msau; Landsberg, Katarina; Shevchenko, Anna; Chávez de Diego, Sebastián; Géli, Vincent (Elsevier, 2006)Set1 is the catalytic subunit and the central component of the evolutionarily conserved Set1 complex (Set1C) that methylates ...
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Article
Publisher correction: Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab (Leukemia, (2021), 35, 1, (201-214), 10.1038/s41375-020-0840-y)
García-Guerrero, Estefanía; Götz, Ralph; Doose, Sören; Sauer, Markus; Rodríguez Gil, Alfonso; Pérez Simón, José Antonio; Danhof, Sophia (Springer Nature, 2022) -
Article
Regulon-Specific Control of Transcription Elongation across the Yeast Genome
Pelechano, Vicent; Jimeno González, Silvia; Rodríguez Gil, Alfonso; García Martínez, José; Pérez Ortín, José E.; Chávez de Diego, Sebastián (Public Library of Science, 2009)Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide ...
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Patent. Invention
Soporte sólido para la unión y/o síntesis química en fase sólida y procedimiento de utilización
Flores Mosquera, María; Rodríguez Gil, Alfonso; Gañán-Calvo, Alfonso M.; Chávez de Diego, Sebastián; Cebolla Ramírez, Ángel (Oficina Española de Patentes y Marcas (OEPM), 2007-08-16)Soporte sólido para la unión y/o síntesis química en fase sólida y procedimiento de utilización. En la presente invención ...
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Article
The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
Rodríguez Gil, Alfonso; Chávez de Diego, Sebastián; García Martínez, José; Géli, Vincent; Muñoz Centeno, María de la Cruz; Pelechano, Vicent; Pérez Ortín, José E. (2010) -
Article
The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation
Millán Zambrano, Gonzalo; Rodríguez Gil, Alfonso; Peñate Salas, Xenia; Miguel Jiménez, María Dolores De; Morillo Huesca, Macarena; Krogan, Nevan; Chávez de Diego, Sebastián (Public Library of Science, 2013)Transcriptional elongation requires the concerted action of several factors that allow RNA polymerase II to advance through ...
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Article
Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab
García-Guerrero, Estefanía; Götz, Ralph; Doose, Sören; Sauer, Markus; Rodríguez Gil, Alfonso; Pérez Simón, José Antonio; Danhof, Sophia (Nature Publishing Group, 2021)Multiple myeloma (MM) is incurable, so there is a significant unmet need for effective therapy for patients with relapsed ...
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Article
Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription
Vanti, Manuela; Gallastegui, Edurne; Respaldiza, Iñaki; Rodríguez Gil, Alfonso; Gómez Herreros, Fernando; Jimeno González, Silvia; Chávez de Diego, Sebastián (Public Library of Science, 2009)Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that ...