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Browsing by Author "Pulido, Marina R."
Now showing items 1-19 of 19
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Article
A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Pachón Díaz, Jerónimo; McConnell, Michael J. (Elsevier, 2020-01)Outer membrane vesicles (OMVs) were isolated from an Acinetobacter strain deficient in lipopolysaccharide (LPS) due to a ...
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Article
Activity of Host Antimicrobials against Multidrug-Resistant Acinetobacter baumannii Acquiring Colistin Resistance through Loss of Lipopolysaccharide
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; Moreno-Martínez, Patricia; Martín-Peña, Reyes; López Rojas, Rafael; Pachón Díaz, Jerónimo; McConnell, Michael J. (American Society for Microbiology, 2014-05)Acinetobacter baumannii can acquire resistance to the cationic peptide antibiotic colistin through complete loss of ...
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Article
Application of BioFire FilmArray Blood Culture Identification panel for rapid identification of the causative agents of ventilator-associated pneumonia
Pulido, Marina R.; Moreno Martínez, P.; González-Galán, V.; Fernández Cuenca, Felipe Manuel; Pascual Hernández, Álvaro; Garnacho Montero, José; Lepe Jiménez, José Antonio; Cisneros, José Miguel (Elsevier, 2018-11)Objective: To evaluate the ability of the BioFire FilmArray Blood Culture Identification (BCID) panel to rapidly detect ...
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Article
Characterization of Extended-Spectrum β-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone
López Cerero, Lorena; Stolz, E.; Pulido, Marina R.; Pascual Hernández, Álvaro (American Society for Microbiology, 2022-07)We describe the first occurrence in Spain of community cases of CTX-M-27-producing Shigella sonnei sequence type 152 ...
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Article
Emerging therapies for multidrug resistant Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; López Rojas, Rafael; Pachón Díaz, Jerónimo; McConnell, Michael J. (Cell Press, 2013-03)The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics ...
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Article
First Steps Towards a Vaccine against Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; McConnell, Michael J. (Bentham Science, 2013)Acinetobacter baumannii has become an important cause of human infections, most notably in the hospital setting. In addition, ...
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Article
Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress
Díaz Díaz, Sara; García Montaner, Andrea; Vanni, Roberta; Murillo Torres, Marina; Recacha, Esther; Pulido, Marina R.; Romero Muñoz, María; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Elsevier, 2024-04-23)In recent years, new evidence has shown that the SOS response plays an important role in the response to antimicrobials, ...
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Article
High incidence of pandrug-resistant Acinetobacter baumannii isolates collected from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial
Nowak, J.; Zander, E.; Stefanik, D.; Higgins, P. G.; Roca, I.; Vila, J.; Cisneros Herreros, José Miguel; Garnacho Montero, José; MagicBullet Working Group WP4; Pulido, Marina R. (Oxford Academic, 2017-12)Objectives: To investigate the molecular epidemiology, antimicrobial susceptibility and carbapenem resistance determinants ...
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Article
Identification of a Stable Chromosomal Tandem Multicopy of bla(VIM-63), a New bla(VIM-2) Carbapenemase
Pulido, Marina R.; García Montaner, Andrea; López Cerero, Lorena; Fernández Cuenca, Felipe Manuel; Gutiérrez-Fernández, José; Pascual Hernández, Álvaro (American Society for Microbiology, 2022-07)This study characterizes a new genetic structure containing a multicopy of a bla(VIM-2) variant with an A676C substitution, ...
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Article
Immunization with Lipopolysaccharide-Deficient Whole Cells Provides Protective Immunity in an Experimental Mouse Model of Acinetobacter baumannii Infection
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; Pachón Díaz, Jerónimo; McConnell, MJ (2014)The increasing clinical importance of infections caused by multidrug resistant Acinetobacter baumannii warrants the ...
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Article
Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Pachón Díaz, Jerónimo; McConnell, Michael J. (Elsevier, 2018-07-05)Outer membrane complex (OMC) vaccines, which contain antigens from the bacterial outer membrane, have been developed for ...
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Article
Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Caro Vega, José Manuel; Pulido, Marina R.; Moreno Martínez, P.; Pachón Díaz, Jerónimo; McConnell, Michael J. (American Society for Microbiology, 2016-08)LpxC inhibitors have generally shown poor in vitro activity against Acinetobacter baumannii. We show that the LpxC inhibitor ...
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Article
Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems
Harding, Christian M.; Pulido, Marina R.; Venanzio, Gisela Di; Kinsella, Rachel L.; Webb, Andrew I.; Scott, Nichollas E.; Pachón Díaz, Jerónimo; Feldman, Mario F. (American Society for Biochemistry and Molecular Biology, Inc., 2017-04-03)Pathogenic Acinetobacter species, including Acinetobacter baumannii and Acinetobacter nosocomialis, are opportunistic human ...
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Article
Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii
Carretero Ledesma, Marta; García Quintanilla, Meritxell de Jesús; Martín-Peña, Reyes; Pulido, Marina R.; Pachón Díaz, Jerónimo; McConnell, M. J. (Taylor & Francis, 2018)Acinetobacter baumannii can acquire resistance to colistin via complete loss of lipopolysaccharide (LPS) biosynthesis due ...
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Article
Progress on the development of rapid methods for antimicrobial susceptibility testing
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Martín-Peña, Reyes; Cisneros Herreros, José Miguel; McConnell, Michael J. (Oxford, 2013-06-30)Antimicrobial susceptibility testing is essential for guiding the treatment of many types of bacterial infections, especially ...
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Dataset
Quantitative study of ESBL and carbapenemase producers in wastewater treatment plants in Spain: a culture-based detection analysis of raw and treated waters [Dataset]
Monge Olivares, Laura; Peñalva Moreno, Germán; Pulido, Marina R.; Garrudo Bárcena, Lara; Doval Aguirre, Miguel Ángel; Ballesta Mudarra, Sofía; Merchante, Nicolás; Rasero del Real, Pablo; Cuberos Gómez, Lucila; Carpes Hortal, Graciano; López Cerero, Lorena (2024-09-06)Background Antibiotics could modify multidrug-resistant microorganisms (MDRO) populations in urban wastewater. Water ...
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Article
RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli
Díaz Díaz, S.; Yerbes, Pilar; Recacha, E.; De Gregorio Iaria, Belén; Pulido, Marina R.; Romero-Muñoz, María; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Elsevier, 2023-02)RecA inhibition could be an important strategy to combat antimicrobial resistance because of its key role in the SOS ...
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Article
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics: study protocol for a randomized controlled trial
Rosso Fernández, Clara; Garnacho Montero, José; Antonelli, M.; Dimopoulos, George; Cisneros Herreros, José Miguel; MagicBullet Working Group WP4; Pulido, Marina R. (BMC, 2015)Background Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and ...
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Article
Synergistic effect of SOS response and GATC methylome suppression on antibiotic stress survival in Escherichia coli
Díaz Díaz, S.; Recacha, E.; Pulido, Marina R.; Romero Muñoz, María; De Gregorio Iaria, Belén; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (https://journals.asm.org/doi/epdf/10.1128/aac.01392-22, 2023-03)The suppression of the SOS response has been shown to enhance the in vitro activity of quinolones. Furthermore, Dam-dependent ...