Browsing by Author "Pérez Simón, José Antonio"
Now showing items 1-20 of 46
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Article
An Active Isodicentric X Chromosome in a Case of Refractory Anaemia with Ring Sideroblasts Associated with Marked Thrombocytosis
(Hindawi, 2014)Refractory anaemia with ring sideroblasts and marked thrombocytosis (RARS-T) is a provisional entity in the World Health ...
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ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype
(Wiley Open Access, 2020)Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its diagnosis is based ...
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PhD Thesis
Cambios en los perfiles de expresión génica en condiciones fisiológicas versus patológicas en el sistema hematopoyético
(2014-12-12)El trabajo realizado en esta tesis doctoral consiste en el estudio de los cambios en la expresión génica que sufren las ...
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CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets
(Elsevier, 2022)Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ...
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Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis
(Nature Publishing Group, 2022)The sympathetic nervous system has been evolutionary selected to respond to stress and activates haematopoietic stem cells ...
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Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial
(Springer, 2021)This analysis from the phase II BRIGHT AML 1003 trial reports the long-term efficacy and safety of glasdegib + ...
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Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib
(Nature Publishing Group, 2022)Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as ...
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Comparison of outcomes for HLA-matched sibling and haplo identical donors in Myelodysplastic syndromes: report from the chronic malignancies working party of EBMT
(Springer Nature, 2022)Myelodysplastic syndromes (MDS) are the second common indication for an Allo-HCT. We compared the outcomes of 1414 matched ...
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Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease
(Nature Publishing Group, 2021-09-23)In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation ...
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Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis
(Elsevier, 2013)Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase ...
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Editorial: Regulatory T cells in graft versus host disease
(Frontiers Media, 2023-02-20)Regulatory T cells (Tregs) are modulators of the immune system that play a key role in maintaining self-tolerance. Treg ...
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PhD Thesis
Efecto inmunomodulador de la vitamina D en el periodo postrasplante alogénico de progenitores hematopoyéticos
(2016-01-22)El presente trabajo de tesis se basa en un ensayo clínico multicéntrico realizado a nivel nacional sobre una población de ...
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Article
Effect of Vitamin D on Graft-versus-Host Disease
(MDPI, 2022)The different cell subsets of the immune system express the vitamin D receptor (VDR). Through the VDR, vitamin D exerts ...
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Evaluation of prognostic factors among patients with chronic graft-versus-host disease
(Ferrata-Storti Foundation, 2011)Background: Chronic graft-versus-host disease (cGVHD) is a major complication after allogeneic stem cell transplantation ...
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Article
Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice
(SAGE Journals, 2015)Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related ...
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PhD Thesis
Inhibición de la vía de señalización Hedgehog con glasdegib en pacientes con enfermedad injerto contra receptor crónica esclerodermiforme: resultados de un ensayo piloto de fase I/II
(2023-03-09)La enfermedad injerto contra receptor crónica esclerodermiforme (EICRcs) se caracteriza por la fibrosis cutánea progresiva ...
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PhD Thesis
Leucemia mieloide aguda con cambios relacionados con mielodisplasia: caracterización citomorfológica, citogenética y molecular, y valor pronóstico de mutaciones en el gen ASXL1
(2023-03-02)La clasificación de las leucemias mieloides agudas (LMA) tiene como objeto la definición de entidades con un perfil ...
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Article
Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases
(MDPI, 2021)Antimicrobial stewardship programs (ASPs) in hematological patients are especially relevant. However, information about ...