Now showing items 1-3 of 3

    • Icon

      Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation  [Article]

      Martínez de Pablos, Rocío; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Muñoz, Mario F.; Machado Quintana, Alberto; Venero Recio, José Luis (BioMed Central, 2014)
      Background: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and is accompanied by an inflammatory reaction that is believed to contribute to its pathogenesis. ...
    • Icon

      Folic acid supplementation: some practical aspects  [Article]

      Cano Rodríguez, María Mercedes; Muñoz, Mario F.; Ayala Gómez, Antonio; Argüelles Castilla, Sandro (Federation of Anti-Aging Medicine Societies, 2012)
      Since 1956, when Harman first postulated the free radical theory of aging, numerous studies have been carried out to test the protective action of antioxidants. One of these protective compounds used in antioxidant therapy ...
    • Icon

      Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal  [Article]

      Ayala Gómez, Antonio; Muñoz, Mario F.; Argüelles Castilla, Sandro (Hindawi Publishing Corporation, 2014)
      Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs). Over the last ...