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Browsing by Author "Muñiz Guinea, Manuel"
Now showing items 1-20 of 31
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Article
A Regulatory Role for cAMP-dependent Protein Kinase in Protein Traffic along the Exocytic Route
Muñiz Guinea, Manuel; Alonso, Manuel; Hidalgo Jiménez, Josefina; Velasco López, Ángel (The American Society for Biochemistry and Molecular Biology, 1996)The influence of protein kinase A activity on transport of newly synthesized vesicular stomatitis virus G glycoprotein along ...
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Article
A Role for Lipids in Protein Sorting?
Aguilera Romero, María Auxiliadora; Muñiz Guinea, Manuel (Swiss Chemical Society, 2021)Lipid and protein diversity provides structural and functional identity to the membrane compartments that define the ...
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Article
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells
Epstein, Sharon; Kirkpatrick, Clare L.; Castillon, Guillaume Alain; Muñiz Guinea, Manuel; Riezman, Isabelle; David, Fabrice P.A.; Wollheim, Claes B.; Riezman, Howard (Elsevier, 2012)Sphingolipids are not only important components of membranes but also have functions in protein trafficking and intracellular ...
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PhD Thesis
Análisis funcional de mecanismos de selección molecular que operan en la ruta secretora temprana
Manzano López, Javier (2013-12-20)Introducción La organización estructural y funcional de la célula eucariota depende, en gran medida, de la actividad de ...
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PhD Thesis
Análisis funcional del complejo p24 en Saccharomyces cerevisiae
Aguilera Romero, María Auxiliadora (2010)El propósito general de esta tesis es el análisis molecular de la función del complejo p24 en los procesos selectivos de ...
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Article
CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets
Medrano, Mayte; Lemus Conejo, Ana; López Martín, Sergio; Millán Linares, María Carmen; Rosillo Ramírez, María de los Ángeles; Muñiz Guinea, Manuel; Calderón Ruíz, Rocío; Pérez Simón, José Antonio; Abia González, María del Rocío (Elsevier, 2022)Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ...
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Article
Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites
Rodríguez Gallardo, Sofía; Kurokawa, Kazuo; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Ikeda, Atsuko; Zoni, Valeria; Aguilera Romero, María Auxiliadora; Pérez Linero, Ana María; López Martín, Sergio; Muñiz Guinea, Manuel (American Association for the Advancement of Science, 2020)Protein sorting in the secretory pathway is crucial to maintain cellular compartmentalization and homeostasis. In addition ...
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PhD Thesis
Control de calidad de la exportación selectiva del retículo endoplásmico mediada por lípidos
Sabido Bozo, Susana (2022-11-18)El transporte selectivo de proteínas a lo largo de la ruta secretora (sorting) es un proceso esencial para mantener la ...
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Article
Crosslinking assay to study a specific cargo-coat interaction through a transmembrane receptor in the secretory pathway
Manzano López, Javier; Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Pérez Linero, Ana María; Cordones Romero, Antonio; Aguilera Romero, María Auxiliadora; Lucena Hernández, Rafael; López Martín, Sergio; Muñiz Guinea, Manuel (Public Library of Science, 2022)Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and ...
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Article
Determination of the lipid composition of the GPI anchor
Aguilera Romero, María Auxiliadora; Sabido Bozo, Susana; López Martín, Sergio; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Pérez Linero, Ana María; Riezman, Isabelle; Riezman, Howard; Muñiz Guinea, Manuel (PLOS, 2021)In eukaryotic cells, a subset of cell surface proteins is attached by the glycolipid glycosylphosphatidylinositol (GPI) ...
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Article
Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum
López Martín, Sergio; Pérez Linero, Ana María; Manzano López, Javier; Sabido Bozo, Susana; Cortés Gómez, Alejandro; Rodríguez Gallardo, Sofía; Aguilera Romero, María Auxiliadora; Goder, Veit; Muñiz Guinea, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic ...
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Article
Endoplasmic Reticulum Export of GPI-Anchored Proteins
López Martín, Sergio; Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Muñiz Guinea, Manuel (MDPI, 2019)Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat ...
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PhD Thesis
Estudio de la organización compleja de tejidos biológicos usando conceptos matemáticos
Sánchez Gutiérrez, Daniel (2015-12-17) -
Article
Limited ER quality control for GPI-anchored proteins
Sikorska, Natalia; Lemus Rodríguez,Leticia; Aguilera Romero, María Auxiliadora; Manzano López, Miguel A.; Muñiz Guinea, Manuel; Goder, Veit (Rockefeller University Press, 2016)Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation ...
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Article
Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function
García Rodríguez, Néstor; Manzano López, Javier; Muñoz Bravo, Miguel; Fernández García, Elisabet; Muñiz Guinea, Manuel; Wellinger, Ralf Erik (American Society for Biochemistry and Molecular Biology, 2015)Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss ...
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Article
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
Kajiwara, Kentaro; Ikeda, Atsuko; Aguilera Romero, María Auxiliadora; Castillon, Guillaume Alain; Kagiwada, Satoshi; Muñiz Guinea, Manuel; Funato, Kouichi (Company of Biologists Ltd, 2014)Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ...
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PhD Thesis
Papel de los receptores de carga en la organización funcional de la ruta secretora temprana
Pérez Linero, Ana María (2016-10-07)Introducción La organización estructural y funcional de la célula eucariota depende, en gran medida, de la actividad de ...
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Article
Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
Muñiz Guinea, Manuel; Martín Rubio, María Esther; Hidalgo Jiménez, Josefina; Velasco López, Ángel (National Academy of Sciences of the USA, 1997)We have examined the role played by protein kinase A (PKA) in vesicle-mediated protein transport from the trans-Golgi ...
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Article
Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites
Rodríguez Gallardo, Sofía; Sabido Bozo, Susana; Ikeda, Atsuko; Araki, Misako; Okazaki, Kouta; Nakano, Miyako; Aguilera Romero, María Auxiliadora; Cortés Gómez, Alejandro; López Martín, Sergio; Waga, Miho; Nakano, Akihiko; Kurokawa, Kazuo; Muñiz Guinea, Manuel; Funato, Kouichi (Elsevier, 2022)Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export ...
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PhD Thesis
Regulación de la estructura y función del complejo de Golgi por factores citosólicos y proteínas G heterotriméricas
Muñiz Guinea, Manuel (1996)Las células eucariotas están organizadas en una serie de compartimentos delimitados por membranas lipídicas. En cada ...