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Browsing by Author "Medrano Padial, Concepción"
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Article
Characterization of NR1J1 Paralog Responses of Marine Mussels: Insights from Toxins and Natural Activators
Casas Rodríguez, Antonio; Medrano Padial, Concepción; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María; Campos, Alexandre; Fonseca, Elza (Multidisciplinary Digital Publishing Institute (MDPI), 2024-06-07)The pregnane X receptor (PXR) is a nuclear hormone receptor that plays a pivotal role in regulating gene expression in ...
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Article
Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Llana Ruiz-Cabello, María; Cătunescu, Giorgiana M.; Moyano Salvago, Rosario; Risalde, María de los Angeles; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Multidisciplinary Digital Publishing Institute (MDPI), 2020)Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and ...
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Article
Cytotoxicity studies of a stilbene extract and its main components intended to be used as preservative in the wine industry
Medrano Padial, Concepción; Puerto Rodríguez, María; Merchán Gragero, María del Mar; Moreno Onorato, Francisco Javier; Richard, Tristan; Cantos Villar, Emma; Pichardo Sánchez, Silvia (Elsevier, 2020)The use of stilbenes has been proposed as an alternative to sulfur dioxide in wine. Provided the feasibility from a ...
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Article
Estilbenos como una alternativa sostenible al anhídrido sulfuroso en vinos
Gutiérrez Escobar, Rocío; Puertas, Belén; Jiménez Hierro, María Jesús; Aliaño González, María José; Medrano Padial, Concepción; Pichardo Sánchez, Silvia; Richard, Tristan; Cantos Villar, Emma (EDP Sciences, 2023-11-23)El anhídrido sulfuroso (SO2) es el conservante más empleado en la industria agroalimentaria y enológica por sus propiedades ...
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PhD Thesis
Estilbenos como una alternativa sostenible al anhídrido sulfuroso en vinos. Evaluación de la toxicidad del extracto de estilbeno
Medrano Padial, Concepción (2021-03-05)La demanda de los consumidores por alimentos cada vez más naturales está creando una tendencia creciente en la industria ...
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Final Degree Project
Evaluación de la genotoxocidad de un compuesto del extracto de proallium ap® mediante el ensayo cometa con potencial uso en el envase alimentario.
Medrano Padial, Concepción (2016)Con el fin de reducir el uso de conservantes sintéticos, la industria alimentaria ha comenzado a desarrollar nuevos sistemas ...
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Article
Genotoxicity evaluation of graphene derivatives by a battery of in vitro assays
Cebadero Domínguez, Óscar; Medrano Padial, Concepción; Puerto Rodríguez, María; Sánchez Ballester, Soraya; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (Elsevier, 2023)The interest of graphene materials has increased markedly in the recent years for their promising applications in many ...
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Dataset
Genotoxicity evaluation of graphene in vitro assays [dataset]
Cebadero Domínguez, Óscar; Medrano Padial, Concepción; Puerto Rodríguez, María; Sánchez Ballester, Soraya; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (2023-12-20)The aim of this study was to assess the potential mutagenicity and genotoxicity of graphene oxide (GO) and reduced-graphene ...
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Article
Genotoxicity Evaluation of Two Derived Products from Allium Extracts: s-propylmercaptocysteine and s-propyl Mercaptoglutathione
Cascajosa Lira, Antonio; Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Baños, Alberto; de la Torre, José M.; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2023)Propyl-propane-thiosulfonate (PTSO) is one of the main organosulfur compounds present in Allium essential oils with a ...
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Article
Identification of in vitro metabolites of an Allium organosulfur compound and environmental toxicity prediction as part of its risk assessment
Cascajosa Lira, Antonio; Medrano Padial, Concepción; Pichardo Sánchez, Silvia; Torre, José Manuel de la; Baños, Alberto; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María (Elsevier, 2023)Propyl-propane-thiosulfonate (PTSO) is an organosulfur compound found inAllium spp. Due to its antioxidant and antimicrobial ...
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Article
In vitro assessment of the mutagenic and genotoxic potential of a pure stilbene extract
Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Puerto Rodríguez, María; Pichardo Sánchez, Silvia (Elsevier, 2021-04)Stilbenes are secondary metabolites of great interest produced by many plant species due to their important bioactive ...
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Article
In Vitro Mutagenic and Genotoxic Assessment of Anatoxin-a Alone and in Combination with Cylindrospermopsin
Plata Calzado, Cristina; Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Cameán Fernández, Ana María; Jos Gallego, Ángeles Mencía (MDPI, 2023)Anatoxin-a (ATX-a) is a cyanobacterial toxin whose occurrence has been reported worldwide and has attracted increasing ...
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Article
In Vitro Toxicity Assessment of Stilbene Extract for Its Potential Use as Antioxidant in the Wine Industry
Medrano Padial, Concepción; Puerto Rodríguez, María; Moreno Onorato, Francisco Javier; Richard, Tristan; Cantos Villar, Emma; Pichardo Sánchez, Silvia (MDPI, 2019)The reduction of sulfur dioxide in wine is a consumer’s demand, considering the allergic effects that may occur in people ...
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Article
In Vivo Genotoxicity Evaluation of a Stilbene Extract Prior to Its Use as a Natural Additive: A Combination of the Micronucleus Test and the Comet Assay
Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Ayala, Nahúm; Beaumont, Pauline; Rouger, Caroline; Krisa, Stéphanie; Pichardo Sánchez, Silvia; Puerto Rodríguez, María (MDPI, 2021)Genotoxic data of substances that could be used as food additives are required by the European Food Safety Authority. In ...
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Article
Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad
Guzmán Guillén, Remedios; Puerto Rodríguez, María; Pichardo Sánchez, Silvia; Jos Gallego, Ángeles Mencía; Cameán Fernández, Ana María; Díez-Quijada Jiménez, Leticia; Medrano Padial, Concepción; Cascajosa Lira, Antonio; Cebadero Domínguez, Óscar; Casas Rodríguez, Antonio; Plata Calzado, Cristina; Prieto Ortega, Ana Isabel (Real e Ilustre Colegio Oficial de Farmacéuticos de Sevilla, 2023)Las “Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias ...
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Article
Oral Administration of Tipranavir with Long-chain Triglyceride Results in Moderate Intestinal Lymph Targeting but no Efficient Delivery to HIV-1 Reservoir in Mesenteric Lymph Nodes
Chu, Y.; Qin, C.; Feng, W.; Sheriston, C.; Khor, Y.; Medrano Padial, Concepción; Watson, B. E.; Chan, T.; Ling, B.; Stocks, M. J.; Fischer, P. M.; Gershkovich, P. (Elsevier, 2021)The introduction of combination antiretroviral therapy (cART) led to substantial improvement in mortality and morbidity ...
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Article
Protection and reversion role of a pure stilbene extract from grapevine shoot and its major compounds against an induced oxidative stress
Medrano Padial, Concepción; Puerto Rodríguez, María; Richard, Tristan; Cantos Villar, Emma; Pichardo Sánchez, Silvia (Elsevier, 2021)Sulfur dioxide is a controversial preservative used in winemaking. Given its potential toxicity, it is of great interest ...
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Article
Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach
Qin, Chaolong; Chu, Yen Ju; Feng, Wanshan; Fromont, Christophe; He, Sijia; Ali, Joseph; Lee, Jong Bong; Zgair, Atheer; Medrano Padial, Concepción; Fischer, Peter M.; Gershkovich, Pavel (Elsevier, 2021)The combined antiretroviral therapy (cART) can efficiently suppress HIV replication, but the cessation of cART usually ...
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Article
Toxicological Evaluation of Piceatannol, Pterostilbene, and ε-Viniferin for Their Potential Use in the Food Industry: A Review
Medrano Padial, Concepción; Prieto Ortega, Ana Isabel; Puerto Rodríguez, María; Pichardo Sánchez, Silvia (MDPI, 2021)The application of stilbenes in the food industry is being considered because of their biological activities. Piceatannol, ...