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Browsing by Author "McConnell, Michael J."
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Article
A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Pachón Díaz, Jerónimo; McConnell, Michael J. (Elsevier, 2020-01)Outer membrane vesicles (OMVs) were isolated from an Acinetobacter strain deficient in lipopolysaccharide (LPS) due to a ...
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Activity of Host Antimicrobials against Multidrug-Resistant Acinetobacter baumannii Acquiring Colistin Resistance through Loss of Lipopolysaccharide
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; Moreno-Martínez, Patricia; Martín-Peña, Reyes; López Rojas, Rafael; Pachón Díaz, Jerónimo; McConnell, Michael J. (American Society for Microbiology, 2014-05)Acinetobacter baumannii can acquire resistance to the cationic peptide antibiotic colistin through complete loss of ...
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Emerging therapies for multidrug resistant Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; López Rojas, Rafael; Pachón Díaz, Jerónimo; McConnell, Michael J. (Cell Press, 2013-03)The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics ...
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First Steps Towards a Vaccine against Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Pulido, Marina R.; McConnell, Michael J. (Bentham Science, 2013)Acinetobacter baumannii has become an important cause of human infections, most notably in the hospital setting. In addition, ...
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Article
Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Pachón Díaz, Jerónimo; McConnell, Michael J. (Elsevier, 2018-07-05)Outer membrane complex (OMC) vaccines, which contain antigens from the bacterial outer membrane, have been developed for ...
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Article
Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii
García Quintanilla, Meritxell de Jesús; Caro Vega, José Manuel; Pulido, Marina R.; Moreno Martínez, P.; Pachón Díaz, Jerónimo; McConnell, Michael J. (American Society for Microbiology, 2016-08)LpxC inhibitors have generally shown poor in vitro activity against Acinetobacter baumannii. We show that the LpxC inhibitor ...
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Positive Predictive Value of Leeds Acinetobacter Medium for Environmental Surveillance of Acinetobacter baumannii
McConnell, Michael J.; Pérez-Romero, Pilar; Lepe Jiménez, José Antonio; Pérez Ordóñez, Ana; Valencia, R.; Vázquez Barba, Isabel; Pachón Díaz, Jerónimo (American Society of Microbiology, 2011)Infections caused by Acinetobacter baumannii often occur in outbreaks during which the bacteria are spread through contact ...
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Progress on the development of rapid methods for antimicrobial susceptibility testing
Pulido, Marina R.; García Quintanilla, Meritxell de Jesús; Martín-Peña, Reyes; Cisneros Herreros, José Miguel; McConnell, Michael J. (Oxford, 2013-06-30)Antimicrobial susceptibility testing is essential for guiding the treatment of many types of bacterial infections, especially ...
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Quantitative Real-Time PCR for Detection of Acinetobacter baumannii Colonization in the Hospital Environment
McConnell, Michael J.; Pérez Ordóñez, Ana; Pérez-Romero, Pilar; Valencia, R.; Lepe Jiménez, José Antonio; Vázquez-Barba, Isabel; Pachón Díaz, Jerónimo (American Society of Microbiology, 2012)A real-time PCR assay was developed for detecting the presence of Acinetobacter baumannii on hospital equipment and compared ...