idUS - Browsing by Author "Kelly, Geoff"

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Article

Molecular basis of FIR-mediated c-myc transcriptional control

Cukier, Cyprian D.; Hollingworth, David; Martin, Stephen; Kelly, Geoff; Díaz Moreno, Irene; Ramos, Andrés (Nature Research, 2010)

The far upstream element (FUSE) regulatory system promotes a peak in the concentration of c-Myc during cell cycle. First, ...
Article

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

Díaz Moreno, Irene; Hollingworth, David; Kelly, Geoff; Martin, Stephen; García Mayoral, María Flor (Oxford University Press, 2010)

KSRP is a multi-domain RNA-binding protein that recruits the exosome-containing mRNA degradation complex to mRNAs coding ...
Article

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

Díaz Moreno, Irene; Hollingworth, David; Frenkiel, Thomas A.; Kelly, Geoff; Martin, Stephen; Howell, Steven; García Mayoral, María Flor; Gherzi, Roberto; Briata, Paola; Ramos, Andrés (Nature Research, 2009)

The AU-rich element (ARE)-mediated mRNA-degradation activity of the RNA binding K-homology splicing regulator protein ...