Now showing items 1-6 of 6

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      Cell Death Related Proteins Beyond Apoptosis in the CNS 

      Bahatyrevich Kharitonik, Bazhena; Medina Guzmán, Rafael; Flores Cortés, Alicia; García Cruzado, Marta; Kavanagh, Edel T.; Burguillos García, Miguel Ángel (Frontiers Media S.A., 2022)
      Cell death related (CDR) proteins are a diverse group of proteins whose original function was ascribed to apoptotic cell ...
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      Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model 

      Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015)
      Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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      Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation 

      Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015)
      Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
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      Microglia: Agents of the CNS Pro-Inflammatory Response 

      Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
      The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
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      Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia 

      Kavanagh, Edel T.; Rodhe, Johanna; Burguillos García, Miguel Ángel; Venero Recio, José Luis; Joseph, Bertrand (Nature Publishing Group, 2014)
      The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...
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      Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke 

      Rodhe, Johanna; Burguillos García, Miguel Ángel; Martínez de Pablos, Rocío; Kavanagh, Edel T.; Persson, Annette; Englund, Elisabet; Venero Recio, José Luis (BioMed Central, 2016)
      Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...