Browsing by Author "Joseph, Bertrand"
Now showing items 1-6 of 6
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Article
Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
(Impact Journals, LLC, 2015)Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Article
Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
(2015)Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
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Article
Microglia: Agents of the CNS Pro-Inflammatory Response
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...
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Article
Microglial subtypes: diversity within the microglial community
(EMBO Press, 2019)Microglia are brain-resident macrophages forming the first active immune barrier in the central nervous system. They fulfill ...
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Article
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
(BioMed Central, 2015)Background We have uncovered a caspase-dependent (caspase-8/caspase-3/7) signaling governing microglia activation and ...
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Article
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
(Nature Publishing Group, 2014)The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...