Browsing by Author "Jiménez Cortegana, Carlos"
Now showing items 1-18 of 18
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Article
Circulating immune biomarkers in peripheral blood correlate with clinical outcomes in advanced breast cancer
(Nature Publishing Group, 2021-07-13)Identification of the different elements intervening at the tumor microenvironment seems key to explain clinical evolution ...
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Article
Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
(BMJ, 2021)Background The search for immunological markers with ability of predicting clinical outcome is a priority in lymphomas, ...
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PhD Thesis
Estudio poblaciones celulares en pacientes con linfoma difuso de células B grandes refractarios o en recaída: papel de las células supresoras de origen mieloide en respuesta al tratamiento R2-GDP
(2020-07-13)La inmunoedición, que se caracteriza por el escape que realizan las células malignas de la inmunovigilancia antitumoral, ...
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Article
Lenalidomide plus R-GDP (R2-GDP) in Relapsed/ Refractory Diffuse Large B-Cell Lymphoma: Final Results of the R2-GDP-GOTEL Trial and Immune Biomarker Subanalysis
(AMER ASSOC CANCER RESEARCH, 2022)Purpose: New therapeutic options are needed in relapsed/refrac tory diffuse large B-cell lymphoma (R/R DLBCL). Lenalidomide ...
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Article
Leptin, both bad and good actor in cancer
(MDPI, 2021)Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in obesity. Leptin exerts many ...
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Article
Low levels of granulocytic myeloid-derived suppressor cells may be a good marker of survival in the follow-up of patients with severe COVID-19
(Frontiers Media S.A., 2022)Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease (coronavirus disease 2019, ...
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Article
Lower Survival and Increased Circulating Suppressor Cells in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma with Deficit of Vitamin D Levels Using R-GDP Plus Lenalidomide (R2-GDP): Results from the R2-GDP-GOTEL Trial
(MDPI, 2021-09-15)The search of prognostic factors is a priority in diffuse large B-cell lymphoma (DLBCL) due to its aggressiveness. We ...
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Article
Myeloid-derived suppressor cells and vaccination against pathogens
(Frontiers Media, 2022-09-29)It is widely accepted that the immune system includes molecular and cellular components that play a role in regulating and ...
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Article
NK cells and solid tumors therapeutic potential and persisting obstacles
(BMC, 2022-11-01)Natural killer (NK) cells, which are innate lymphocytes endowed with potent cytotoxic activity, have recently attracted ...
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Article
Nutrients and Dietary Approaches in Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease: A Narrative Review
(MDPI, 2021-11-19)Cardiovascular disease (CVD) is the most common cause of morbidity and mortality in developed countries. The prevalence ...
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Article
Obesity and Risk for Lymphoma: Possible Role of Leptin
(MDPI, 2022-12-08)Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
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Article
Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin
(MDPI AG, 2022)Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of ...
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Article
Pembrolizumab Plus Gemcitabine in the Subset of Triple-Negative Advanced Breast Cancer Patients in the GEICAM/2015-04 (PANGEA-Breast) Study
(MDPI, 2021-10-29)The PANGEA-Breast trial evaluated a new chemo-immunotherapeutic combination that would synergistically induce long-term ...
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Article
Possible Role of Leptin in Atopic Dermatitis: A Literature Review
(MDPI, 2021-11-05)Atopic dermatitis (AD) is the most frequent chronic inflammatory skin disease, and its incidence has been rapidly increasing ...
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Article
Role of Leptin as a Link between Asthma and Obesity: A Systematic Review and Meta-Analysis
(MDPI, 2022-12-29)Asthma and obesity are considered as highly prevalent diseases with a great impact on public health. Obesity has been ...
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Article
Role of leptin in non-alcoholic fatty liver disease
(MDPI, 2021-06-30)Non-alcoholic fatty liver disease (NAFLD), which affects about a quarter of the global population, poses a substantial ...
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Article
The effects of dendritic cell-based vaccines in the tumor microenvironment Impact on myeloid-derived suppressor cells
(Frontiers Media, 2022-11-15)Dendritic cells (DCs) are a heterogenous population of professional antigen presenting cells whose main role is diminished ...
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Article
Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics
(MDPI, 2022)Lymphoma is a neoplasm arising from B or T lymphocytes or natural killer cells characterized by clonal lymphoproliferation. ...